inflammation

blood cells
January 7, 2016

Immune tolerance in endothelial cells

Inducing “tolerance” to bacterial toxins in the endothelial cells that line blood vessels may offer a new approach for preventing the negative consequences of sepsis.

By Leigh MacMillan
October 29, 2015

Inflammation, obesity and diabetes

Vanderbilt study adds to the mounting role for inflammatory signaling in obesity.

By Leigh MacMillan
October 2, 2015

The yin and yang of COX-2

New findings add to the understanding of how the enzyme COX-2 works, which is critical to the development of COX-2-targeted anti-inflammatory drugs.

By Sanjay Mishra
September 4, 2015

Vitamin C protects blood vessel lining

Dietary vitamin C may maintain healthy blood vessels in patients with inflammatory diseases.

By Leigh MacMillan
July 23, 2015

Study explores protein’s role in inflammation-associated cancer

An antioxidant protein may protect against colon cancer that develops in patients with inflammatory bowel disease, suggesting new strategies for reducing colon cancer risk in these patients.

By Leigh MacMillan
January 9, 2015

Does fish oil help prevent A-fib?

Growing evidence suggests that fish oil, thought to directly prevent inflammation, oxidative stress and heart disease, may have limited clinical utility.

By VUMC News and Communications
November 24, 2014

Gene influences allergies in asthma

A particular gene is associated with a specific type of inflammatory response in people with asthma – a finding that could suggest new therapeutic targets for treating asthma.
By VUMC News and Communications
November 21, 2014

Host sequesters zinc to control stomach bug

Understanding how zinc and the host’s immune response control H. pylori’s cancer-causing potential could suggest new therapeutic strategies to reduce infection and cancer risk.
By Leigh MacMillan
October 28, 2014

Peptide quells “genomic storm”

A cell-penetrating peptide developed at Vanderbilt blocks the signaling pathways that lead to lethal shock caused by bacterial infection.
By T.J. Utset
September 18, 2014

Dioxin, fathers and preterm birth

Exposure of male mice to the pollutant dioxin causes preterm birth across multiple generations, suggesting that efforts to prevent preterm birth should include pre-conception interventions for dads.
By VUMC News and Communications
August 1, 2014

Anti-inflammatory protein “rheostat” sheds light on leaky blood vessels

Vanderbilt researchers have discovered that the protein CRADD counteracts inflammatory injury to endothelial cells, which could assist the development of new therapies for inflammatory vascular disorders.
By Emily Poulin
February 12, 2014

Obesity sends immune cells to the brain

Obesity causes peripheral immune cells to move to the brain, where they may contribute to inflammation and the pathophysiology of obesity.
By Leigh MacMillan
December 12, 2013

Therapeutic target for gastric cancer

A protein kinase linked to inflammation and tumor development may be a good target for gastric cancer therapies.
By Leigh MacMillan