inflammation

July 23, 2015

Study explores protein’s role in inflammation-associated cancer

An antioxidant protein may protect against colon cancer that develops in patients with inflammatory bowel disease, suggesting new strategies for reducing colon cancer risk in these patients.

By Leigh MacMillan
January 9, 2015

Does fish oil help prevent A-fib?

Growing evidence suggests that fish oil, thought to directly prevent inflammation, oxidative stress and heart disease, may have limited clinical utility.

By VUMC News and Communications
November 24, 2014

Gene influences allergies in asthma

A particular gene is associated with a specific type of inflammatory response in people with asthma – a finding that could suggest new therapeutic targets for treating asthma.

By VUMC News and Communications
November 21, 2014

Host sequesters zinc to control stomach bug

Understanding how zinc and the host’s immune response control H. pylori’s cancer-causing potential could suggest new therapeutic strategies to reduce infection and cancer risk.

By Leigh MacMillan
October 28, 2014

Peptide quells “genomic storm”

A cell-penetrating peptide developed at Vanderbilt blocks the signaling pathways that lead to lethal shock caused by bacterial infection.

By T.J. Utset
September 18, 2014

Dioxin, fathers and preterm birth

Exposure of male mice to the pollutant dioxin causes preterm birth across multiple generations, suggesting that efforts to prevent preterm birth should include pre-conception interventions for dads.

By VUMC News and Communications
August 1, 2014

Anti-inflammatory protein “rheostat” sheds light on leaky blood vessels

Vanderbilt researchers have discovered that the protein CRADD counteracts inflammatory injury to endothelial cells, which could assist the development of new therapies for inflammatory vascular disorders.
By Emily Poulin
February 12, 2014

Obesity sends immune cells to the brain

Obesity causes peripheral immune cells to move to the brain, where they may contribute to inflammation and the pathophysiology of obesity.
By Leigh MacMillan
December 12, 2013

Therapeutic target for gastric cancer

A protein kinase linked to inflammation and tumor development may be a good target for gastric cancer therapies.
By Leigh MacMillan
October 11, 2013

New target for stopping inflammation

Importin alpha 5, a member of a family of proteins that “shuttle” other proteins into the nucleus, is a potential new target for drugs to treat inflammatory diseases.
By Bill Snyder
August 9, 2013

‘Yo-yo dieting’ inflames fat tissue

Gaining and losing weight during “yo-yo dieting” may contribute to an exaggerated immune response in fat tissue that increases metabolic dysfunction more than steady weight gain alone.
By Leigh MacMillan
August 8, 2013

Nuclear shield against cell death

The protein SARM appears to protect cells from inflammation-driven death by stabilizing the nuclear laminin scaffold.
By Bill Snyder
November 6, 2012

Bacterial signals in sarcoidosis

Study adds evidence for infectious agents’ role in sarcoidosis, an inflammatory condition that can lead to respiratory failure and death.
By VUMC News and Communications
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