Jim Cassat

December 19, 2023

Three from VUMC elected to ASCI

Three physician scientists from Vanderbilt University Medical Center have been elected this year to membership in the American Society for Clinical Investigation, one of the nation’s oldest and most respected medical honor societies.

By Bill Snyder
Research by Christopher Peek, PhD, left, Jim Cassat, MD, PhD, and their colleagues reveals how gut inflammation leads to bone loss.
August 25, 2022

Vanderbilt researchers discover how gut inflammation leads to bone loss

Gastrointestinal inflammation, such as occurs in inflammatory bowel disease, triggers the expansion of a population of “bone-eating” cells, leading to bone loss.

By Leigh MacMillan
Jim Cassat, MD, PhD, and colleagues are studying enzymes involved in metabolism that are particularly important for Staphylococcus aureus to survive in host tissues.
July 7, 2022

Mathers Foundation award supports study of crosstalk between skeletal, immune systems

Vanderbilt’s Jim Cassat, MD, PhD, has received a three-year, $750,000 award from the G. Harold and Leila Y. Mathers Foundation to support research exploring the interplay between bone homeostasis and infectious disease.

By Leigh MacMillan
Jim Cassat, MD, PhD, and colleagues are studying enzymes involved in metabolism that are particularly important for Staphylococcus aureus to survive in host tissues.
June 3, 2020

Study explores how staph bacteria can survive in bone

A comprehensive evaluation of the metabolic pathways that support Staphylococcus aureus (“staph”) growth during invasive bone infections could offer new targets for treatment.

By Leigh MacMillan
April 18, 2019

Medical Societies honor multiple Vanderbilt faculty

Several Vanderbilt faculty members were recently honored during the joint annual meeting of the Association of American Physicians (AAP) and American Society for Clinical Investigation (ASCI).

By Bill Snyder
March 15, 2018

New imaging approach offers unprecedented views of staph infection

A new integrated imaging approach makes it possible to probe the molecules involved in invasive infections and can be broadly applied to any health or disease state.

By Leigh MacMillan
December 4, 2014

Physician-scientist is dream job for Vanderbilt’s Cassat

Jim Cassat, M.D., Ph.D., a pediatric infectious disease specialist who joined the Vanderbilt faculty this summer, loves taking care of children with bone infections and doing research to understand the host-pathogen interactions during these invasive infections.
By Leigh MacMillan
October 16, 2014

Staph ‘gangs’ share nutrients during infection: study

Antibiotic-resistant bacteria can share resources to cause chronic infections, Vanderbilt investigators have discovered. The findings shed light on a long-standing question in infectious diseases and may inform new treatment strategies.
By Leigh MacMillan
July 31, 2014

Cassat lands Burroughs Wellcome Fund award

James Cassat, M.D., Ph.D., assistant professor of Pediatrics and Pathology, Microbiology and Immunology, has received a Burroughs Wellcome Fund (BWF) Career Award for Medical Scientists.
By Leigh MacMillan
June 20, 2013

Studies outline new model for staph bone infections

Osteomyelitis, a debilitating bone infection most frequently caused by Staphylococcus aureus (“staph”) bacteria, is particularly challenging to treat.
By Leigh MacMillan