Journal of Lipid Research Archives
A critical skin enzyme
May. 18, 2023—Detailed studies of the enzymatic properties of PNPLA1 support the requirement for this protein in skin barrier formation.
A new view of a cholesterol carrier
Feb. 7, 2023—Vanderbilt researchers developed a novel method to measure small RNAs carried by HDL and demonstrated that these molecules circulate in greater concentrations than previously believed and are likely to contribute to communication between immune cells.
The yin and yang of cell signaling
Feb. 14, 2019—Larry Marnett and colleagues have explored the role of two enzymes in metabolizing molecules associated with cell proliferation, inflammatory processes and neurological diseases.
How the skin protects
Apr. 19, 2018—Treatments for common skin conditions such as atopic dermatitis may be improved by understanding the enzymes responsible for forming the skin’s water-tight barrier.
Inhibiting obesity
Sep. 15, 2017—An enzyme in the gut – NAPE-PLD – is required for the action of signaling molecules that reduce food intake and weight gain.
Platelet protein modification
Jan. 13, 2016—Vanderbilt investigators have identified a new biomarker to assess platelet function.
Protein implicated in atherosclerosis
Nov. 25, 2014—Vanderbilt researchers have discovered a new target for the prevention of atherosclerotic plaque development and cardiovascular disease.
An orphan enzyme’s purpose
Oct. 4, 2012—“Orphan” enzyme may play role in cancer growth, new research suggests.
Obesity turns “good” cholesterol bad
Mar. 21, 2012—Studies offer new insights into how obesity impairs the function of HDL, the “good” cholesterol.
Reversing lipid woes in cystic fibrosis
Mar. 3, 2012—Abnormal levels of fatty acids in the blood and tissues of patients with cystic fibrosis may be reversed by supplementation with the fatty acids DHA and EPA.
