kidney disease

Insulin in vials
November 11, 2021

New way to bEET insulin resistance

Signaling molecules called EETs could improve insulin resistance, a primary risk factor for Type 2 diabetes and cardiovascular disease, Vanderbilt researchers have discovered.

By Bill Snyder
Roy Zent, MBBCh, PhD, left, Fabian Bock, MD, PhD, and colleagues are studying the factors involved in the maintenance and integrity of the kidney collecting duct.
November 4, 2021

Harrison Society researcher discovers key regulator of kidney cell structure

New research from Vanderbilt could aid efforts to promote kidney regeneration after injury or to develop engineered organs.

By Leigh MacMillan
August 5, 2021

Gene expression in diabetic nephropathy

Vanderbilt researchers are looking to mRNA populations in podocytes — kidney cells that help filter blood — to help identify potential targets for treating diabetic kidney disease.

By Shivani Sharma
March 25, 2021

Spirituality may help reduce end-stage kidney disease risk

Researchers from Vanderbilt’s Division of Nephrology and Hypertension have identified an under-studied characteristic that may have a protective effect on end-stage kidney disease (ESKD) risk among vulnerable populations.

By Emily Stembridge
October 5, 2020

Clue to diabetic kidney disease

Vanderbilt researchers have identified a signaling pathway that promotes kidney fibrosis in patients with diabetes — and that could be targeted with an existing approved medication.

By Sarah E. Glass
June 4, 2020

Protecting the injured kidney

Leslie Gewin and colleagues have upended conventional dogma about Wnt/beta-catenin signaling in the kidney, finding that it protects against chronic kidney disease rather than promoting it.

By Leigh MacMillan
May 18, 2020

Implant one day may replace dialysis

Vanderbilt researchers used pharmacological manipulations to increase salt and water transport by kidney cells grown in culture, a step necessary for realizing an implantable artificial kidney device.
By Anivarya Kumar
February 13, 2020

Nashville VA dialysis unit named in Stone’s honor

The Nashville Veterans Affairs Medical Center has dedicated its dialysis unit to William Stone, MD, a nephrologist and professor of Medicine at VUMC
By Kelsey Herbers
January 28, 2020

Protein levels in urine after acute kidney injury predict future loss of kidney function

High levels of protein in a patient’s urine after acute kidney injury is associated with increased risk of kidney disease progression, Vanderbilt researchers report.
By Kelsey Herbers
October 31, 2019

Acute kidney injury recovery time impacts future risk

Interventions that impact the timing of recovery following acute injury may improve future outcomes for patients.
By Danielle Kopke
October 3, 2019

Diabetes drug study explores cardiovascular risks for patients with kidney disease

An observational study using medical record information from nearly 50,000 U.S. military veterans sheds new light on which drugs are best for patients with Type 2 diabetes and one of its common complications, kidney disease.
By Paul Govern
September 25, 2019

Study shines light on architecture of kidney disease

A study of 280,000 U.S. veterans, including 56,000 African Americans, has identified in greater detail than ever before the genetic architecture of kidney function and chronic kidney disease (CKD), according to researchers at Vanderbilt University Medical Center and their colleagues.
By Bill Snyder
July 25, 2019

Sex differences in kidney injury

Men are more susceptible to progressive kidney disease than women; new VUMC studies point to differences in the expression and activation of the EGF receptor.
By Kelsey Herbers