kidney disease

Gene expression in diabetic nephropathy

Vanderbilt researchers are looking to mRNA populations in podocytes — kidney cells that help filter blood — to help identify potential targets for treating diabetic kidney disease.

Spirituality may help reduce end-stage kidney disease risk

Researchers from Vanderbilt’s Division of Nephrology and Hypertension have identified an under-studied characteristic that may have a protective effect on end-stage kidney disease (ESKD) risk among vulnerable populations.

Clue to diabetic kidney disease

Vanderbilt researchers have identified a signaling pathway that promotes kidney fibrosis in patients with diabetes — and that could be targeted with an existing approved medication.

Group’s efforts lead to removal of race as a variable in common test of kidney function

A group of Vanderbilt students, residents and faculty — connected through their passion for health equity — have identified and worked together to rectify longstanding concerns about the inappropriate use of race as a variable in the calculation of estimated glomerular filtration rate (eGFR), which estimates a patient’s level of kidney function and helps determine the stage of kidney disease.

Protecting the injured kidney

Leslie Gewin and colleagues have upended conventional dogma about Wnt/beta-catenin signaling in the kidney, finding that it protects against chronic kidney disease rather than promoting it.

Implant one day may replace dialysis

Vanderbilt researchers used pharmacological manipulations to increase salt and water transport by kidney cells grown in culture, a step necessary for realizing an implantable artificial kidney device.

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