Matthew Tyska Archive — Page 1 of 1

Sleeping newborn baby lying on their side on a bed, with one arm bent near the face and soft natural light falling across the scene.
April 4, 2025

Study details genetic architecture of congenital diarrheal disorders in infants

The findings represent a significant advance toward development of more effective, targeted therapies for congenital diarrhea and enteropathies

Close-up of a researcher looking through a white laboratory microscope, with additional laboratory equipment and a handheld tool visible in the background.
March 27, 2025

Six Vanderbilt faculty elected fellows of international scientific society

One of the world’s largest multidisciplinary scientific societies, the AAAS also publishes the Science family of journals.

Fluorescence microscopy image showing bright orange-purple actin structures forming long, finger-like protrusions from a tuft cell.
November 26, 2024

What’s all the tuft about?

Vanderbilt researchers used advanced imaging techniques to detail the microscopic structure of intestinal tuft cells, highlighting their unique organization of the structural protein actin.

The research team studying undiagnosed congenital diarrheas includes, from left, Matt Tyska, PhD, James Goldenring, MD, PhD, Joseph Roland, PhD, Sari Acra, MD, MPH, and Hernan Correa, MD.
October 24, 2019

Team set to study undiagnosed congenital diarrhea in infants

Researchers at four institutions, including Vanderbilt, have been awarded a five-year, $9.4 million federal grant to tackle undiagnosed congenital diarrheas caused by a single gene mutation.

Fluorescent multicolored microscopic structures resembling clustered crystals or fibers against a black background.
September 19, 2019

Microvilli in motion

Live cell imaging studies have revealed that microvilli — finger-like protrusions on the surface of epithelial cells — move and collide as they form the brush border.

Super-resolution microscopy image of mouse intestine showing a curved band of white microvilli tipped with yellow cadherin; red cell nuclei appear below against a dark background.
February 14, 2019

Adhesion protein optimizes border

Matthew Tyska and colleagues have found that an adhesion protein plays a key role in building the intestinal brush border that is essential for absorbing nutrients.