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Ming-Zhi Zhang Archives

Inflammatory driver of obesity

Aug. 25, 2022—Blocking the EGF receptor signaling pathway in immune system macrophages represents a new target for improving insulin resistance in people with obesity.

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Study sheds light on the dark side of obesity

May. 12, 2022—Vanderbilt research that promotes the anti-inflammatory pathway in macrophages could also reduce some of the bad side effects of obesity.

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Gene expression in diabetic nephropathy

Aug. 5, 2021—Vanderbilt researchers are looking to mRNA populations in podocytes — kidney cells that help filter blood — to help identify potential targets for treating diabetic kidney disease.

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Sex differences in kidney injury

Jul. 25, 2019—Men are more susceptible to progressive kidney disease than women; new VUMC studies point to differences in the expression and activation of the EGF receptor.

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Immune system a must for kidney repair

Nov. 12, 2015—A signaling protein that is essential for recovery from acute kidney injury works by increasing the population of tissue-repairing immune cells.

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Study sheds light on side effects of COX-2 drugs

Oct. 22, 2015—A team of Vanderbilt University Medical Center scientists are closer to understanding why COX-2 inhibitors — drugs that relieve arthritis pain and inflammation without the gastrointestinal side effects of other painkillers — cause heart problems in some patients. Now

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Do-it-yourself repair in the kidney

Jan. 31, 2013—The kidney can mediate its own repair through proliferation of resident immune system cells.

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Recent Stories from VUMC News and Communications Publications

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Hope
Momentum
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