New England Journal of Medicine

December 10, 2025

Sedative choice could improve outcomes for breathing tube patients

It’s the first study to demonstrate cardiovascular risks of high doses of ketamine (low blood pressure, arrhythmia), side effects that have not been well studied in the past.

By Craig Boerner
July 17, 2025

New organ recovery technique could make more heart transplants available

The method, rapid recovery with extended ultra-oxygenated preservation, involves flushing the donor heart with a cold oxygenated preservation solution after death.

By Matt Batcheldor
May 19, 2025

New study highlights improved treatment approach for people with mild asthma

A multicenter trial found that adding budesonide, an inhaled steroid, to albuterol significantly reduced severe asthma attacks compared to using albuterol alone.

By Christina Echegaray
(iStock image)
May 18, 2025

Study finds navigational bronchoscopy as effective and safer alternative to transthoracic biopsy for lung nodules  

Each year, millions of lung nodules are detected during routine X-rays or CT scans.

By Craig Boerner and Holly Fletcher 
April 4, 2025

Study details genetic architecture of congenital diarrheal disorders in infants

The findings represent a significant advance toward development of more effective, targeted therapies for congenital diarrhea and enteropathies

By Bill Snyder
March 4, 2025

Skin tone may affect accuracy of blood oxygen measurement in children: study

One of two commonly used oximetry devices failed to detect low oxygen levels in 7% of patients with the darkest skin tone.

By Bill Snyder
February 27, 2025

VUMC part of new study validating curative therapy for sickle cell disease

Of 38 adults with severe SCD who participated in the study, more than 97% no longer required immunosuppressive therapy one year after the transplant.
By Bill Snyder
August 22, 2024

Yelena Bodien joins VUMC to advance efforts in research, treatment of brain disorders

Bodien, who will co-direct the Neuroimaging Core of the Critical Illness, Brain Dysfunction and Survivorship Center, has applied behavioral measures and advanced neuroimaging to improve the diagnosis and prognosis of severe brain injury.
By Jill Clendening
June 13, 2024

Multicenter study identifies method of preoxygenation that prevents hypoxemia and cardiac arrest during emergency tracheal intubation

Preoxygenation is the administration of supplemental oxygen prior to the start of a procedure to increase the content of oxygen in the lung and decrease the risk of hypoxemia
By Nancy Humphrey
March 26, 2024

GRADE Study expands results of major NIH-sponsored comparative study of glucose lowering medications in Type 2 diabetes

The study, which included more than 5,000 volunteers with Type 2 diabetes from diverse racial and ethnic groups, compared the treatments insulin glargine, liraglutide, glimepiride and sitagliptin.
June 16, 2023

Study shows video laryngoscope increases successful intubation on first attempt

A Vanderbilt study study comparing the two types of laryngoscopes used in tracheal intubation of critically ill patients showed that the use of a video laryngoscope increased successful intubation on the first attempt, compared to the use of a direct laryngoscope, the standard approach for almost a century.
By Nancy Humphrey
March 30, 2023

New procedure helps patients avoid leg amputation

More than 75% of patients facing amputation from the most severe form of peripheral artery disease were able to keep their limb after an innovative treatment as part of a multicenter study published in the New England Journal of Medicine.
By Craig Boerner
March 2, 2023

High-dose flu vaccine beneficial for pediatric stem cell transplant patients

Vanderbilt was the lead site for an influenza vaccine study in pediatric allogeneic hematopoietic stem cell transplant recipients that may lead to a change in the current flu vaccine recommendations in this vulnerable population.
By Jessica Pasley