Vanderbilt Genetics Institute Archive — Page 2 of 4

Portrait of a smiling woman with short light-brown hair, wearing a dark turtleneck and long beaded necklace against a brown background.
July 26, 2023

Nancy Cox receives American Society of Human Genetics Leadership Award

Nancy Cox, PhD, director of the Vanderbilt Genetics Institute, is the recipient of the 2023 ASHG Leadership Award from the American Society of Human Genetics.

Stylized blue profile of a human face formed from a wireframe grid, merging with glowing circuit-board traces and digital data patterns.
May 9, 2023

Neural networks probe proteins

A machine learning method based on neural networks outperformed a mutational scanning model at identifying disease-causing mutations in an Alzheimer’s disease protein, suggesting the method could be useful for facilitating therapeutic design.

Silhouette of a person facing a glowing DNA double helix, overlaid with floating binary digits in a blue-toned digital composition.
April 20, 2023

Genetics and chronic pain

Polygenic risk scores — scores that reflect the influence of common genetic variants — could be used to predict the likelihood of developing chronic overlapping pain conditions and guide biomarker and targeted prevention efforts.

Futuristic blue digital illustration combining a DNA double helix with glowing circuit-board patterns, binary-style numbers, and vertical data streams.
March 28, 2023

Inflammation implicated in exfoliation syndrome

Computational genetics tools have implicated inflammatory pathways in exfoliation syndrome, the most common cause of secondary glaucoma, which can result in blindness.

Alexander Bick, MD, PhD, and colleagues are studying inflammation at the single-cell level in the rare disease RUNX1-FPD.
January 12, 2023

Chan Zuckerberg Initiative grant supports single-cell study of rare inherited disease

A multidisciplinary team led by Vanderbilt University Medical Center investigator Alexander Bick, MD, PhD, has been awarded a $2 million, four-year grant to study inflammation at the single-cell level in the rare disease RUNX1-FPD.

Manual blood pressure monitor with a blue cuff, round pressure gauge, black inflation bulb, and attached stethoscope on a white background.
May 19, 2022

Genetics and blood pressure

Including polygenic risk scores for blood pressure may improve predictive models to identify people at risk for treatment-resistant hypertension.