Researchers found that increased sedentary behavior in aging adults was associated with worse cognition and brain shrinkage in areas related to risk for developing Alzheimer’s disease.

The study sets out how gene expression that drives the formation of new blood vessels exhibits different patterns, cell by cell, in the brains of people with Alzheimer's disease.

The 5th Annual Vanderbilt Alzheimer's Disease Research Day, sponsored by the Vanderbilt Memory and Alzheimer's Center (VMAC), was held April 10 at Vanderbilt University School of Nursing.

MRI brain scans at baseline for study participants 60 and older — who were free of clinical dementia at study entry — predicted a decline in independent function five years later.

New findings from Vanderbilt neurologists suggest that cardiovascular disease may increase the spaces surrounding blood vessels in the brain and lead to cognitive decline.

Vanderbilt researchers found that a protein with roles in innate immunity worsens memory at baseline in carriers of APOE-e4, the strongest genetic risk factor for Alzheimer’s disease, further implicating neuroinflammation in cognitive decline.

Fewer Black, Hispanic and Asian patients meet biomarker qualifications for landmark treatments that may slow the progression of Alzheimer’s disease by targeting amyloid plaques, according to new findings published in JAMA Neurology.