Research

October 22, 2015

Study sheds light on side effects of COX-2 drugs

A team of Vanderbilt University Medical Center scientists are closer to understanding why COX-2 inhibitors — drugs that relieve arthritis pain and inflammation without the gastrointestinal side effects of other painkillers — cause heart problems in some patients.

Now

By Bill Snyder
September 30, 2015

Reduced-nicotine cigarettes decreased dependence and frequency of smoking: NEJM study

Reduced-nicotine cigarettes were beneficial in reducing nicotine exposure and dependence, and also the number of cigarettes smoked per day, when compared with standard-nicotine cigarettes in a six-week study published in the New England Journal of Medicine.

By Craig Boerner
September 23, 2015

Data diving for health

To most effectively use electronic health records for research, investigators should query multiple components of the record to identify patients with specific diseases.

By VUMC News and Communications
August 26, 2015

Framework for studying cell responses

Vanderbilt investigators have developed a framework for studying cellular responses that could be used to identify the agents driving a range of biological processes in health and disease.

By Leigh MacMillan
model of DNA double helix
August 20, 2015

New type of trial shows promise for several cancers

Anti-cancer drugs are typically tested on one type of cancer at a time. But an international consortium of cancer investigators, including Vanderbilt-Ingram Cancer Center (VICC) researchers, simultaneously tested an existing therapy in patients with several different forms of cancer that all exhibit the same tumor gene mutation.

By VUMC News and Communications
August 13, 2015

Macara lands award to explore cancer cell behavior

Vanderbilt’s Ian Macara, Ph.D., has won an Outstanding Investigator Award from the National Cancer Institute (NCI) — nearly $6.6 million over seven years — to support the “unusual potential” of his research, which seeks to understand and predict cancer cell “behavior.”

By Bill Snyder
August 13, 2015

VUMC study shifts thinking on how bone fractures heal

New findings show that fibrin, a protein that was thought to play a key role in fracture healing, is not required, shifting understanding of how fractures heal.
By Leigh MacMillan
August 6, 2015

New targeted therapy shows promise for rare joint tumor

Vanderbilt-Ingram Cancer Center (VICC) investigators and colleagues at several major medical centers have been testing a new targeted therapy that is showing promise for the treatment of a rare tumor that forms in and around joint cavities.
By VUMC News and Communications
July 30, 2015

Study sheds light on human gut’s ‘pacemaker’ cells

The gut has its own built-in pacemakers, populations of specialized cells that control smooth muscle contraction in the stomach, small intestine and colon.
By Bill Snyder
July 30, 2015

Worldwide Cancer Research lauds Macara’s contributions

Ian Macara, Ph.D., professor and chair of the Department of Cell and Developmental Biology, recently returned from Scotland, where he received this year’s Colin Thomson Memorial Medal for his contributions to cancer research.
By VUMC News and Communications
July 23, 2015

Study explores protein’s role in inflammation-associated cancer

An antioxidant protein may protect against colon cancer that develops in patients with inflammatory bowel disease, suggesting new strategies for reducing colon cancer risk in these patients.
By Leigh MacMillan
July 9, 2015

Signals of schizophrenia

Vanderbilt researchers have discovered a possible molecular mechanism of schizophrenia that could lead to new treatments for the disorder.
By VUMC News and Communications
July 9, 2015

Study could lead to vaccine for mosquito-borne dengue virus

Researchers at Vanderbilt University and the National University of Singapore have determined the structure of a human monoclonal antibody which, in an animal model, strongly neutralizes a type of the potentially lethal dengue virus.
By Bill Snyder
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