Research

November 11, 2022

Study finds inherited link to appendix cancer

A Vanderbilt study is the first to show inherited risk factors for appendiceal cancer.

By Tom Wilemon
Jacek Hawiger, MD, PhD, third from right, with study team members, from left, Katherine Gibson-Corley, DVM, PhD, Yan Liu, MD, Jozef Zienkiewicz, PhD, Huan Qiao, MD, PhD, and Ruth Ann Veach.
November 10, 2022

Hawiger still blazing a trail in inflammation research

Vanderbilt research describes a new investigational peptide drug that can penetrate immune and nonimmune cells, and block inflammatory signaling in a preclinical model of atopic dermatitis — eczema.

By Bill Snyder
The clinical trial group includes, from left, Gordon Bernard, MD, Katherine Cahill, MD, Kevin Niswender, MD, PhD, Pingsheng Wu, PhD, and R. Stokes Peebles, MD.
November 10, 2022

Clinical trial at VUMC tests novel treatment for asthma

VUMC has begun enrolling patients with asthma in a clinical trial of a novel treatment: a medication approved to treat diabetes and obesity.

By Leigh MacMillan
November 10, 2022

Study defines role of steroids in congenital heart disease surgery

Steroids are commonly given to infants during open-heart surgery to reduce inflammation, but whether the drugs significantly improve patient outcomes has not been settled — until now.

By Bill Snyder
November 8, 2022

Alzheimer’s risk factor and cognition

Vanderbilt researchers found that a protein with roles in innate immunity worsens memory at baseline in carriers of APOE-e4, the strongest genetic risk factor for Alzheimer’s disease, further implicating neuroinflammation in cognitive decline.

By Leigh MacMillan
November 7, 2022

Gene mutations impair gut barrier

Mutations in a cell membrane transporter protein impair the integrity of the gut lining, contributing to chronic gastrointestinal distress for people with the mutations, Vanderbilt researchers report.

By Kelsey Pinckard
November 4, 2022

Study finds Moderna’s COVID-19 vaccine safe and effective for young children

A Vanderbilt study finds that Moderna’s COVID-19 vaccine is safe and effective in children 6 months to 5 years of age.
By Bill Snyder
November 3, 2022

C. diff infections drop in children

The number of pediatric infections caused by Clostridioides difficile (C. diff) decreased from 2013 to 2019, likely due to an increase in antibiotic stewardship programs and improved hospital contact protocols, Vanderbilt researchers found.
By Sarah E. Glass
November 3, 2022

Social behavior brain circuitry

Vanderbilt researchers have identified a novel mechanism regulating social behavior: Neuropeptide Y signaling in the nucleus accumbens brain region.
By Leigh MacMillan
November 3, 2022

Study explores possible drug target for neurological problems

A team at Case Western Reserve University and Vanderbilt University Medical Center has determined with atomic-level precision how two established drugs bind to and alter the conformation of a cell membrane transporter protein called NKCC1, shutting down its activity.
By Paul Govern
November 3, 2022

Event to spotlight VUMC’s COVID-19 research efforts

The public is invited to listen in as scientists on the forefront of COVID-19 research at Vanderbilt University Medical Center share their personal stories on Wednesday afternoon, Nov. 16, in 214 Light Hall.
By Bill Snyder
October 28, 2022

VUMC mourns loss of noted hypertension expert Elijovich

Fernando Elijovich, MD, professor of Medicine in the Division of Clinical Pharmacology at Vanderbilt University Medical Center, died in Nashville on Oct. 21. He was 77.
By Bill Snyder
October 27, 2022

Translational Research Forum highlights range of studies

The 2022 Vanderbilt Translational Research Forum exemplified the range of studies conducted at Vanderbilt University Medical Center that are translating scientific discovery into clinical practice.
By Bill Snyder
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