Research

Eunyoung Choi, PhD, James Goldenring, MD, PhD, and colleagues are studying the development of cancer in the stomach and esophagus.
September 1, 2022

Grant supports research to study gastric cancer origins

Vanderbilt researchers have received $5 million in funding from a new initiative by the National Cancer Institute that aims to define how gastric and gastroesophageal junction adenocarcinomas form and evolve at the cellular level.

By Tom Wilemon
August 30, 2022

A new mechanism for lupus

Vanderbilt researchers describe a new mechanism for the most common form of lupus and suggest a new treatment approach to this autoimmune disease.

By Leigh MacMillan
August 29, 2022

Blood cancer progression

Vanderbilt researchers used single-cell technologies to explore the accumulation of mutations during blood cancer progression, which could help identify strategies for preventing leukemia before it occurs.

By Leigh MacMillan
VUMC’s new automated biobanking system can store as many as 10 million biospecimens.
August 25, 2022

New high-tech biobank safeguards critical specimens

By Bill Snyder
Research by Christopher Peek, PhD, left, Jim Cassat, MD, PhD, and their colleagues reveals how gut inflammation leads to bone loss.
August 25, 2022

Vanderbilt researchers discover how gut inflammation leads to bone loss

Gastrointestinal inflammation, such as occurs in inflammatory bowel disease, triggers the expansion of a population of “bone-eating” cells, leading to bone loss.

By Leigh MacMillan
Maria Hadjifrangiskou, PhD, Connor Beebout, PhD, and colleagues are studying why the bacterium E. coli is so tenacious.
August 25, 2022

Study describes how E. coli co-opts cells, causes recurrent UTIs

Researchers at Vanderbilt University Medical Center have discovered why the uropathogenic bacterium E. coli, the leading cause of urinary tract infections, is so tenacious; their findings could lead to new ways to prevent recurrent UTIs.

By Bill Snyder
August 25, 2022

Rheumatoid arthritis and heart disease: a common path

An increase in certain antibodies in patients with rheumatoid arthritis can serve as a predictive biomarker for cardiovascular disease, Vanderbilt researchers have discovered.
By Bill Snyder
August 25, 2022

Inflammatory driver of obesity

Blocking the EGF receptor signaling pathway in immune system macrophages represents a new target for improving insulin resistance in people with obesity.
By Sarah E. Glass
August 25, 2022

Neurologic complications common in children hospitalized with COVID

Vanderbilt researchers have found another reason to vaccinate children against COVID-19: to help reduce the likelihood of neurologic complications caused by the virus.
By Jessica Pasley
August 18, 2022

Study seeks to explore drug link to fetal vessel defect

Vanderbilt researchers have received a grant to study whether drugs given to premature infants in the neonatal intensive care unit (NICU) contribute to a potentially lethal condition called patent ductus arteriosus.
By Bill Snyder
August 17, 2022

Vanderbilt Prize winner Lehmann’s Discovery Lecture postponed

Ruth Lehmann, PhD, recipient of the 2022 Vanderbilt Prize in Biomedical Science, will deliver her Vanderbilt Prize Discovery Lecture at 4 p.m. Thursday, Sept. 1, in 208 Light Hall.
By Bill Snyder
August 17, 2022

Researchers discover how salt increases blood pressure

A Vanderbilt research team has discovered that activation of a certain protein complex involved in the inflammatory response in immune cells contributes to salt-sensitive hypertension.
By Leigh MacMillan
August 16, 2022

Nanoparticles boost anti-cancer immunity

An ingenious targeted nanoparticle approach developed by Vanderbilt researchers reduced tumor burden in a model of ovarian cancer.
By Bill Snyder
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