Research

Jim Cassat, MD, PhD, and colleagues are studying enzymes involved in metabolism that are particularly important for Staphylococcus aureus to survive in host tissues.
June 3, 2020

Study explores how staph bacteria can survive in bone

A comprehensive evaluation of the metabolic pathways that support Staphylococcus aureus (“staph”) growth during invasive bone infections could offer new targets for treatment.

By Leigh MacMillan
May 27, 2020

Darby lands award for research on complex human behaviors

For outstanding contributions to research in behavioral neurology, Ryan Darby, MD, assistant professor of Neurology, has won the 2020 Norman Geschwind Prize in Behavioral Neurology from the American Academy of Neurology (AAN).

By Paul Govern
May 27, 2020

Target trials support drug safety in pregnant patients

Out of concern for fetal safety, pregnant people have typically been excluded from drug trials. And when human health is on the line, drug studies assessing fetal safety in animal models may be viewed as far from definitive.

By Paul Govern
Research assistant Mahsa Majedi loads reagent used in DNA sample preparation in the genomics lab. She is part of a team of more than a dozen people at VUMC who are “sprinting” to develop — within 90 days — an antibody-based treatment to stop the spread of the Zika virus.
May 21, 2020

VUMC research ramps up in COVID-19 transition

As Nashville cautiously begins to emerge from its two-month-long COVID-19 Safer at Home response, so too are the labs and facilities at Vanderbilt University Medical Center.

By Bill Snyder
This is a 3D volume rendering of an MRI of a post-mortem heart obtained from a patient with COVID-19, acquired at ultra-high 500 micron spatial resolution.
May 21, 2020

Team uses imaging to study ways the heart is affected by coronavirus

Researchers are using imaging and diagnostic pathology to examine postmortem hearts donated by victims of COVID-19 to gain a better understanding of how the coronavirus that causes COVID-19 affects the heart.

By Leigh MacMillan
Research assistant Mahsa Majedi loads reagent used in DNA sample preparation in the genomics lab. She is part of a team of more than a dozen people at VUMC who are “sprinting” to develop — within 90 days — an antibody-based treatment to stop the spread of the Zika virus.
May 19, 2020

VUMC Research Enterprise begins ramping up

As Nashville cautiously begins to emerge from its two-month-long COVID-19 Safer at Home response, so too are the labs and facilities at Vanderbilt University Medical Center.

By Bill Snyder
May 19, 2020

Probing innate immunity

Manuel Ascano team validates an inhibitor of the cGAS-STING signaling pathway, which is important for cellular innate immunity against bacteria, viruses, and our own damaged DNA.
By Leigh MacMillan
May 18, 2020

Implant one day may replace dialysis

Vanderbilt researchers used pharmacological manipulations to increase salt and water transport by kidney cells grown in culture, a step necessary for realizing an implantable artificial kidney device.
By Anivarya Kumar
May 14, 2020

Antibodies eye Pacific Island “fever”

Vanderbilt Vaccine Center team isolates monoclonal antibodies against Ross River virus, which causes rash, fever and debilitating muscle and joint pain lasting three to six months.
By Bill Snyder
May 14, 2020

The adaptable anthrax bacterium

Vanderbilt researchers discover how anthrax bacterium defends itself against structural damage and resists the toxicity of the antimicrobial drug targocil.
By Leigh MacMillan
May 14, 2020

Yin receives early investigator MERIT Award from NCI

Zhijun Yin, PhD, assistant professor of Biomedical Informatics at Vanderbilt University Medical Center, has received the National Cancer Institute’s Method to Extend Research in Time Award (or MERIT Award) for Early Stage Investigators.
By Paul Govern
May 12, 2020

Pioneering nephrologist William Stone mourned

William J. Stone, MD, nephrologist and professor of Medicine, emeritus, who retired in December after 50 years as a member of the faculty of the Vanderbilt University School of Medicine, died Monday, May 11, at his home in Nashville. He was 83.
By Bill Snyder
May 7, 2020

New method captures early viral-host protein interactions

Researchers have developed a method to identify the primary interactions between incoming viral RNA genomes and host proteins.
By Bill Snyder
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