Research

October 3, 2019

Team discovers one more piece to the autism puzzle

Vanderbilt investigators have linked genetic mutations in a single receptor to epilepsy, autism and intellectual disability.

By Bill Snyder
October 3, 2019

A step toward gastric cancer

New research findings provide insight into the detrimental events that develop in response to H. pylori infection.

By Sanjay Mishra
October 3, 2019

A catalog of DNA replication proteins

Vanderbilt scientists have identified 593 proteins that are enriched at sites of DNA duplication and chromatin packaging of newly synthesized DNA.

By Leigh MacMillan
October 3, 2019

Diabetes drug study explores cardiovascular risks for patients with kidney disease

An observational study using medical record information from nearly 50,000 U.S. military veterans sheds new light on which drugs are best for patients with Type 2 diabetes and one of its common complications, kidney disease.

By Paul Govern
October 2, 2019

Research team sorts out drug screen false positive results

Vanderbilt investigators have identified 13 previously unknown drug compounds that cause false positive screenings for amphetamines, buprenorphine (an opioid), cannabinoids and methadone.

By Paul Govern
October 1, 2019

Pua lands NIH Director’s New Innovator Award

Heather Pua, MD, PhD, one of 60 investigators to receive the 2019 NIH Director’s New Innovator Award, will explore a novel type of cell signaling by RNAs in allergic airway inflammation.

By Leigh MacMillan
September 25, 2019

Study shines light on architecture of kidney disease

A study of 280,000 U.S. veterans, including 56,000 African Americans, has identified in greater detail than ever before the genetic architecture of kidney function and chronic kidney disease (CKD), according to researchers at Vanderbilt University Medical Center and their colleagues.
By Bill Snyder
September 25, 2019

Study identifies targeted therapy’s cardiac risks

After a recent study showed that chronic lymphocytic leukemia patients who received ibrutinib as a frontline treatment had a 7% death rate, a new study offers a clearer picture on the reasons for the deaths.
By Tom Wilemon
September 24, 2019

Nobel laureate Südhof set for Oct. 3 Discovery Lecture

Nobel laureate Thomas Südhof, MD, whose studies of synaptic formation and transmission are advancing understanding of brain disorders including autism, Alzheimer’s disease and schizophrenia, will deliver the next Flexner Discovery Lecture on Thursday, Oct. 3.
By Bill Snyder
September 24, 2019

Treating C. diff: new purpose for an old drug?

An inexpensive generic drug once used to prevent gastrointestinal ulcers in people taking daily NSAIDs protects against C. diff infection in mice.
By Paul Govern
September 23, 2019

Tailoring treatment for heart defect

By defining the clinical and genetic factors that predict treatment response, Vanderbilt investigators aim to personalize therapy for a common heart complication in preterm infants.
By Leigh MacMillan
September 20, 2019

Guengerich, Sanders-Bush named ASPET fellows

Vanderbilt University’s F. Peter (Fred) Guengerich, PhD, and Elaine Sanders-Bush, PhD, are among 22 prominent scientists named this week to the inaugural class of fellows of the American Society for Pharmacology and Experimental Therapeutics (ASPET).
By Bill Snyder
September 19, 2019

Microvilli in motion

Live cell imaging studies have revealed that microvilli — finger-like protrusions on the surface of epithelial cells — move and collide as they form the brush border.
By Anivarya Kumar
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