Leigh MacMillan

DNA image

New class of DNA repair enzyme discovered

A new class of DNA repair enzyme has been discovered which demonstrates that a much broader range of damage can be removed from the double helix in ways that biologists did not think were possible.

Inflammation, obesity and diabetes

Vanderbilt study adds to the mounting role for inflammatory signaling in obesity.

Biomarker for intestinal tumors

A new marker could be useful for diagnosing and treating neuroendocrine tumors of the small intestines.

Potential target for lung cancer therapy

The glutamine transporter protein appears to contribute to the survival of lung cancer cells, suggesting it may be a useful diagnostic biomarker and target for therapies.

Collaboration seeks to develop new therapies for bone, other diseases

La Jolla Pharmaceutical Co. and Vanderbilt University have signed a research and license agreement covering Vanderbilt’s research program and intellectual property rights related to compounds that block bone morphogenetic protein (BMP) type-I receptors. The compounds have therapeutic potential in a broad range of diseases, including rare genetic disorders.

conceptual - glowing cell

Tolerating a transplant

A new genetic model has generated new strategies for promoting tolerance to transplants – and improving long-term transplant outcomes – in the background of autoimmune disease.

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