inflammation

January 27, 2020

A new contributor to atherosclerosis

Sean Davies and colleagues are exploring lipid aldehydes produced during oxidative stress and their contribution to HDL dysfunction and atherosclerosis.

By Leigh MacMillan
January 23, 2020

Insights on diabetic retinopathy

A drug that targets multiple pathogenic steps in diabetic retinopathy may be an ideal therapeutic strategy for the disease, Vanderbilt researchers report.

By Leigh MacMillan
December 20, 2019

Reversing stress-related anxiety

Inhibiting COX-2 — an enzyme associated with inflammation — could provide a novel therapeutic approach for stress-related psychiatric disorders.

By VUMC News and Communications
November 5, 2019

Endotoxin shock protector

A novel tool developed by Vanderbilt scientists protects animals from endotoxin shock and can be used for mechanistic analyses of inflammation due to microbial and other insults.

By Bill Snyder
October 17, 2019

Less inflammation = better healing

Immune cells that produce an anti-inflammatory factor are enriched in fat tissue around the heart and may be good targets to improve heart attack outcomes.

By Bill Snyder
3d rendering white blood cells with red blood cells
October 8, 2019

A new regulator of B cell development

New findings establish a role for the pro-inflammatory molecule IL-33 in the early development of antibody-producing B cells.

By Leigh MacMillan
October 1, 2019

Pua lands NIH Director’s New Innovator Award

Heather Pua, MD, PhD, one of 60 investigators to receive the 2019 NIH Director’s New Innovator Award, will explore a novel type of cell signaling by RNAs in allergic airway inflammation.
By Leigh MacMillan
September 19, 2019

Study seeks factors that increase risk of toxicant exposure

Vanderbilt researchers hope to identify factors that may make humans more susceptible to toxicant exposure — specifically the presence of pre-existing inflammatory disease.
By Kelsey Herbers
August 15, 2019

Protein’s role in inflammation-related cancer studied

Investigators are exploring the molecular mechanisms behind the association of chronic inflammation and colon cancer.
By Tom Wilemon
August 8, 2019

New window on fibrosis

A previously unrecognized role for a cell surface receptor may open new therapeutic options for the treatment of fibrotic diseases.
By Bill Snyder
July 30, 2019

Intestinal immune cell interactions

Understanding the roles of various immune cells that reside in the gut lining could shed light on inflammatory bowel diseases.
By Leigh MacMillan
July 18, 2019

Madhur receives Presidential Early Career Award

Meena Madhur, MD, PhD, has received a Presidential Early Career Award for Scientists and Engineers.
By Leigh MacMillan
April 25, 2019

Receptor’s role in stopping H. pylori

The immune receptor NOD1 may be a prime target for preventing or treating H. pylori infections — the most significant risk factor for stomach cancer, Vanderbilt researchers have discovered.
By Niyati Vachharajani
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