Leigh MacMillan Archive — Page 25 of 85

Illustration of purple, textured spherical particles floating against a deep blue background, with bright rays radiating from several larger particles.
August 24, 2021

Autoimmunity advance

Vanderbilt researchers have developed a high-throughput screening method to identify and characterize antigen-specific B cells — potential biomarkers for autoimmune disease and targets for new treatments.

Three rows of tissue microscopy panels showing stained tissue sections alongside separate blue, green, and red fluorescence channels and merged overlays with outlined regions.
August 19, 2021

Expression atlas for cell regulators

Vanderbilt researchers report a comprehensive tissue-specific atlas of protein and mRNA expression for p63 and p73, members of the p53 family signaling network that is the most frequent target of mutations in human cancers.

Mariana Byndloss, DVM, PhD, Woongjae Yoo, PhD, and colleagues are studying how a high-fat diet may contribute to heart disease. (Photo taken prior to revised masking guidelines.)
August 12, 2021

Study reveals missing link between high-fat diet, microbiota and heart disease

A high-fat diet disrupts the biology of the gut’s inner lining and its microbial communities — and promotes the production of a metabolite that may contribute to heart disease, according to a study published Aug. 13 in the journal Science.

Amber-colored softgel capsules arranged in a large letter-shaped oval on a dark gray background.
August 10, 2021

Vitamin D impact on disease biomarkers

In a randomized controlled trial, vitamin D supplementation did not improve biomarkers for cardiovascular and metabolic disease.

Three smiling women in traditional-style clothing stand in a row before a dark red background with rows of gold decorative knobs.
July 27, 2021

Prediction models for breast cancer

Vanderbilt researchers developed new prognostic models for breast cancer outcomes and found that adding postdiagnostic weight change as a factor improves the prediction.

Madison Adolph, PhD, left, David Cortez, PhD, and Archana Krishnamoorthy are studying fundamental processes involved in DNA replication.
July 22, 2021

Researchers discover that protein switches functions to regulate DNA replication

Vanderbilt biochemists have discovered what the DNA damage response protein RADX does — and how it does it.