Leigh MacMillan

bacteria microbiome
August 13, 2019

Host-microbe interactions in the gut

Vanderbilt investigators demonstrated that intestinal cells promote beneficial microbe behavior — the findings support developing microbiota-based therapies for intestinal health.

By Leigh MacMillan
yogurt
August 8, 2019

A probiotic treatment for obesity?

Engineered bacteria that produce beneficial compounds — and that could potentially be administered in foods like yogurt — may be a future treatment for obesity and other chronic diseases.

By Leigh MacMillan
Pampee Young, MD, PhD, left, Sarika Saraswati, PhD, and colleagues are studying the different ways fibroblasts function following tissue injury.
August 8, 2019

Cellular engines of wound repair have distinct roles

Vanderbilt investigators have discovered that, in contrast to prevailing dogma, fibroblasts are not all alike; instead, they have distinctive functions following tissue injury.

By Leigh MacMillan
July 30, 2019

Intestinal immune cell interactions

Understanding the roles of various immune cells that reside in the gut lining could shed light on inflammatory bowel diseases.

By Leigh MacMillan
David Cortez, PhD, left, Petria Thompson, Katherine Amidon, Brandt Eichman, PhD, and colleagues are studying how a DNA repair pathway protein shields sites of damage to avoid mutations.
July 25, 2019

Team’s study reveals details of new DNA repair pathway

Investigators have discovered how a DNA repair pathway protein shields sites of damage to avoid mutations and maintain genome integrity.

By Leigh MacMillan
July 18, 2019

Madhur receives Presidential Early Career Award

Meena Madhur, MD, PhD, has received a Presidential Early Career Award for Scientists and Engineers.

By Leigh MacMillan
July 8, 2019

Clinical study tests drug that may prevent cancer metastasis

A clinical study of a drug that may block cancer metastasis is currently enrolling patients at the Vanderbilt-Ingram Cancer Center.
By Leigh MacMillan
June 24, 2019

Early detection of schizophrenia

Inhibited temperament — a tendency to respond to novelty with wariness, fear or caution — may be a risk factor for schizophrenia that could be targeted for preventative interventions.
By Leigh MacMillan
June 24, 2019

Fish oil and cancer prevention

Fish oil supplementation provides a modest but beneficial effect on reducing molecules associated with colorectal cancer development.
By Leigh MacMillan
June 10, 2019

Cell-cell signals in developing heart

Scott Baldwin and colleagues have discovered early signaling events during heart development, findings that could guide cell replacement therapies for heart disease.
By Leigh MacMillan
June 6, 2019

Mouth microbes and colorectal cancer

Microbial species in the mouth could be playing a role in colorectal cancer development, according to new research from epidemiologists at VUMC.
By Leigh MacMillan
May 29, 2019

Study details regulation of a multi-drug transporter

P-glycoprotein distinguishes between chemicals that it will expel from a cell and inhibitors that block its action.
By Leigh MacMillan
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