Leigh MacMillan

May 25, 2017

Study reveals role for stem cells in chronic lung diseases

A novel population of lung stem cells plays an important role in regulating the pulmonary microvasculature — the network of tiny blood vessels where oxygen and carbon dioxide exchange takes place.

By Leigh MacMillan
May 15, 2017

RSV-HRV viral interference

RSV infection reduces the risk of infection with human rhinovirus, which could have implications for vaccine development and prevention strategies for viral respiratory tract infections in infants.

By Leigh MacMillan
Insulin in vials
May 11, 2017

EETs contribute to insulin sensitivity

Interventions that increase circulating levels of compounds called EETs may improve insulin sensitivity and treat hypertension.

By Leigh MacMillan
May 11, 2017

Discovery Lecturer Kandel tackles age-related memory loss

Eric Kandel, M.D., who was awarded the Nobel Prize in 2000 for discovering molecular mechanisms of memory storage, told the crowd at last week’s Flexner Discovery Lecture that he has recently become interested in memory in the aging brain.

By Leigh MacMillan
Insulin in vials
May 3, 2017

Therapeutic targets for diabetes

Vanderbilt investigators have identified novel regulators of insulin-producing beta-cell proliferation and survival, suggesting new targets for the treatment of type 2 diabetes.

By Leigh MacMillan
April 28, 2017

Regulating anxiety in the brain

Two brain signaling pathways have overlapping functions in regulating anxiety, suggesting that therapeutics aimed at one or the other will impact both.

By Leigh MacMillan
April 27, 2017

Nobel laureate and memory expert Kandel set for next Discovery Lecture

Nobel laureate Eric R. Kandel, M.D., renowned for his studies of learning and memory, will give the next Flexner Discovery Lecture on Thursday, May 4.
By Leigh MacMillan
April 27, 2017

Protein structure may aid in treating Alzheimer’s disease

A new protein structure may guide the development of Alzheimer's therapeutics.
By Leigh MacMillan
April 14, 2017

A new mode of DNA repair

Structural details of a protein that removes DNA lesions shed light on fundamental mechanisms of DNA repair.
By Leigh MacMillan
April 3, 2017

Fighting fungal infections

A detailed structural and functional analysis of the yeast protein that is the main target of antifungal drugs will help direct efforts to develop better treatments.
By Leigh MacMillan
March 30, 2017

Molecular motors expert Spudich set for next Discovery Lecture

James Spudich, Ph.D., renowned for his studies of proteins that function as molecular motors, will deliver the next Flexner Discovery Lecture on Thursday, April 6.
By Leigh MacMillan
March 22, 2017

Blocking neuroblastoma cell growth

An inhibitor of cell metabolism may be a good therapeutic target for neuroblastoma, which accounts for about 15 percent of pediatric cancer-related deaths.
By Leigh MacMillan