Leigh MacMillan

Heart illustration thumbnail

Atrial disease and hypertension links

New findings suggest that misfolded proteins accumulate in the heart atria, particularly in patients with hypertension, and may contribute to atrial heart disease.

Target for atherosclerosis therapies

A newly identified “atheroprotective” gene is a tool for exploring plaque pathophysiology and may be a good target for therapies to slow atherosclerosis progression.

Retinal neuron survival in glaucoma

Understanding how the protein TRPV1 helps neurons survive after glaucoma-related stressors could lead to new therapeutic strategies for glaucoma and other neurodegenerative conditions.

Bacterial secretion machinery: 3-D view

New structural findings reveal how “gatekeeper” proteins participate in the secretion systems bacteria use to infect host cells.

Columbia’s Bakken to deliver Flexner Discovery Lecture

Suzanne Bakken, Ph.D., RN, the Alumni Professor of Nursing and professor of Biomedical Informatics at Columbia University, will deliver the next Flexner Discovery Lecture on Thursday, Dec. 11.

Physician-scientist is dream job for Vanderbilt’s Cassat

Jim Cassat, M.D., Ph.D., a pediatric infectious disease specialist who joined the Vanderbilt faculty this summer, loves taking care of children with bone infections and doing research to understand the host-pathogen interactions during these invasive infections.

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