Leigh MacMillan

Insights on lysosomal storage diseases

A novel mechanism could point to new therapies for a group of inherited diseases that share pathological features.

Neurofibromin fine-tunes bone growth

The protein neurofibromin acts as a brake in a signaling pathway that is important in bone development, Vanderbilt researchers have discovered.

New player in neuronal communication

Vanderbilt researchers have discovered a novel mechanism for the development of dendritic spines – sites of nerve cell communication.

RNA defects in multiple sclerosis

Vanderbilt researchers have discovered that profound defects exist in the integrity of structural RNA molecules in patients with relapsing remitting multiple sclerosis.

Team tracks how kidney responds to blood pressure meds

Changes in the kidney can limit the blood pressure-lowering effects of thiazide diuretics, a new study reports.

Stem cells, Wnt signaling explored at Discovery lecture

Our tissues are in a constant state of flux — cells are lost and cells are generated, with local signals and stem cells maintaining the balance, said Roel Nusse, Ph.D., during last week’s Flexner Discovery Lecture.

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