Leigh MacMillan

November 15, 2012

Inherited lung disease no worse in offspring

An inherited lung disease does not appear to have earlier onset and increased severity – a phenomenon called genetic anticipation – in successive generations.

By Leigh MacMillan
November 8, 2012

Nobel laureate Sharp to speak at VUMC

Nobel laureate Phillip Sharp, Ph.D., will deliver the next Flexner Discovery Lecture on Thursday, Nov. 15.

By Leigh MacMillan
November 8, 2012

Symposium to explore diabetes research at VU

“Diabetes at Vanderbilt: From Molecules to People,” a scientific symposium to highlight diabetes research at Vanderbilt, will take place Wednesday, Nov. 14, from 10 a.m. to 2:30 p.m. in the Vanderbilt Student Life Center.

By Leigh MacMillan
November 8, 2012

Kidney woes during heart failure

Levels of the protein NGAL may be a good predictor of worsening kidney function in patients with acute heart failure.

By Leigh MacMillan
October 31, 2012

Protein’s length, flexibility key to infection

The structural architecture of the reovirus attachment protein is required for efficient reovirus infection of host cells.

By Leigh MacMillan
October 23, 2012

Stomach bug alters tumor suppressor

The stomach bug Helicobacter pylori increases forms of a protein that promote tumor development, perhaps explaining how it elevates risk for gastric cancer.

By Leigh MacMillan
October 18, 2012

Gene regulation found to play role in pulmonary hypertension

New findings from Vanderbilt researchers may explain why only some individuals who have inherited mutations that increase risk for pulmonary hypertension actually develop the disease.
By Leigh MacMillan
October 18, 2012

Setting traps to probe gene function

A new method for creating genetic mutations that can be activated at certain times or in specific tissues will enable studies to probe gene function.
By Leigh MacMillan
October 11, 2012

Amish aid search for Alzheimer’s genes

An analysis of Amish populations revealed novel risk genes for late-onset Alzheimer disease.
By Leigh MacMillan
October 5, 2012

Host proteins can control HIV infection

The protein APOBEC3G contributes to spontaneous control of HIV-1 in vivo and may provide therapeutic benefits.
By Leigh MacMillan
October 4, 2012

Proteins help flip tumor’s invasive switch

Vanderbilt investigators have identified how two key components of cancer's invasive "switch" — the series of signaling events that turn on a tumor cell’s invasive behavior — work together.
By Leigh MacMillan
September 25, 2012

Cell entry ports for cold virus

The respiratory virus HMPV uses its fusion (F) protein – which interacts with cellular receptors called integrins – to bind to and enter target cells.
By Leigh MacMillan
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