Leigh MacMillan

HDL cholesterol impaired in kidney disease

HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk.

Seeing light receptor’s interactions

Understanding how the main receptor for light interacts with other signaling molecules may inform new pharmaceutical development.

Nobel laureate Fire set to deliver upcoming Discovery Lecture

Nobel laureate Andrew Fire, Ph.D., will deliver the next Flexner Discovery Lecture on Thursday, Jan. 24.

Study helps define pancreatic cancer’s cellular origins

Vanderbilt and University of California investigators have discovered the “cell of origin” for pancreatic ductal adenocarcinoma, a finding that could lead to early detection methods and new treatments.

By Leigh MacMillan

January 17, 2013

Zinc: a new antibiotic target?

It may be possible to fight hospital-acquired pathogens like Acinetobacter baumannii by targeting the bacterium’s need for the nutrient metal zinc.

By Leigh MacMillan

January 10, 2013

Simulated Mars mission reveals body’s sodium rhythms

Clinical pharmacologist Jens Titze, M.D., and colleagues have discovered that – in contrast to the prevailing dogma – human sodium levels fluctuate rhythmically with 7-day and monthly cycles.