Leigh MacMillan

March 21, 2012

Obesity turns “good” cholesterol bad

Studies offer new insights into how obesity impairs the function of HDL, the “good” cholesterol.

By Leigh MacMillan
March 19, 2012

iPOND method goes fishing for proteins

A new tool will allow researchers to identify proteins involved in DNA replication and damage repair, processes that go awry in cancer.

By Leigh MacMillan
March 3, 2012

Reversing lipid woes in cystic fibrosis

Abnormal levels of fatty acids in the blood and tissues of patients with cystic fibrosis may be reversed by supplementation with the fatty acids DHA and EPA.

By Leigh MacMillan
March 2, 2012

‘Detangler’ binds, bends and cuts DNA

New details on the DNA-cutting activity of topoisomerase II, a target of anti-cancer drugs, could lead to better chemotherapeutic agents.

By Leigh MacMillan
February 20, 2012

Stem cells take heart

Signaling pathway discoveries suggest ways to induce stem cells to become cardiac muscle cells, which could be useful for regenerating damaged heart muscle.

By Leigh MacMillan
Brain image
February 16, 2012

Memory intact in early psychosis

Brain deficits are not present in the early stages of schizophrenia, suggesting it may be possible to delay or prevent the development of brain abnormalities.

By Leigh MacMillan
February 8, 2012

Matchmaker for clinical studies

ResearchMatch.org is a web-based registry that is connecting participants and researchers for clinical studies.
By Leigh MacMillan
February 8, 2012

Tool finds connections in genome data

A new analytical tool points to genes that act together to increase disease risk.
By Leigh MacMillan
January 23, 2012

Alcohol’s molecular mediators

Therapeutic agents focusing on the brain region involved in stress-induced relapse may be effective in preventing relapse in patients with alcohol use disorders.
By Leigh MacMillan
January 20, 2012

Studies shed new light on how nitric oxide is produced

The discovery of a previously unrecognized and pivotal role of enzyme ASL in nitric oxide production could potentially lead to new therapies for babies with pulmonary hypertension.
By Leigh MacMillan
January 20, 2012

Pumping up the pancreas in pregnancy

A strain of mutant mice provide a novel model for studying glucose intolerance and gestational diabetes during pregnancy and suggest that certain molecules may be useful for therapeutic applications.
By Leigh MacMillan
January 5, 2012

Fishing for heart attack repair tools

By Leigh MacMillan
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