Aliquots - Research Briefs

February 27, 2026

‘Kindlins’ are a key to kidney formation

Kindlins regulate cell signaling during the formation of ureteric buds, a key step in the development of the kidneys’ urine collection system.

February 9, 2026

AI finds patient-level statin barriers in clinical notes

A novel AI framework found documented intolerance to statins in 6.4% of all adult patients, contraindications in 0.7%, and statin deferral in 2.9%.

Clostridium difficile bacterium, 3D illustration
January 28, 2026

Gut microbiome differs according to C. diff symptom status

In a study of children with symptomatic or asymptomatic C. diff, symptom status loomed as the strongest association with differences in gut microbial abundance and diversity.

January 5, 2026

AI gets risk wrong in the clinic

Large language models have become far better than you at solving math problems but may still be bad at employing probabilistic terms in medical contexts.

An initiative at VUMC is helping patients recover more quickly from major surgery, leave the hospital earlier and have fewer side effects from their pain management. (photo by Joe Howell)
December 2, 2025

Ketamine fails surgical recovery trial

In a large, placebo-controlled, randomized trial, the pain reliever ketamine posed side effects while failing to aid patient recovery after major surgery.

November 6, 2025

Inflammatory marker could predict response to therapy in bladder pain syndrome

Patients with chronic bladder pain syndrome who had higher baseline levels of the inflammatory molecule IL-1beta had greater overall improvement following cognitive behavioral therapy.