A new mouse model offers insight into the signaling pathways that control oral cancers – and a platform for testing anticancer therapeutics.

Vanderbilt investigators have used a computational biology approach to uncover new cancer drivers and biomarkers of anticancer drug response.

An overactive stress response contributes to the development of insulin resistance in obese individuals, and blocking it may be therapeutically beneficial.

The activity of a certain factor in immune cells is essential for an anti-tumor response, emphasizing the need to consider the effects of anti-cancer therapies on immune cells.

A combination of two types of therapy may be more effective in treating castration-resistant prostate cancer.

A cell-penetrating peptide developed at Vanderbilt blocks the signaling pathways that lead to lethal shock caused by bacterial infection.

Vanderbilt researchers have discovered that certain immune cells contribute to the development of hypertension, suggesting novel targets for treating the disease.