Dysfunction of the endothelial cells that line blood vessels may contribute to delirium and coma in critically ill patients – and could be a target for therapy.

Targeting repair pathways in the lung’s air sacs may be a valuable therapeutic direction for pulmonary fibrosis – the scarring of lung tissue.

Overexpression of a gene that is a common culprit in leukemia induces stem cell-like features in T cells, which may enable the cells to become cancerous.

Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes.

The gene Has2 participates in signaling that is important in developing fingers and toes, and may have relevance for cancer development.

Berberine, an herbal remedy for diarrhea and intestinal parasites, may be useful in colon cancer therapy.

In critically ill patients with sepsis, plasma hemoglobin may be a new indicator of disease severity – and a potential target for treatment with acetaminophen.