A protein involved in repairing DNA damage associated with gastric reflux may play a tumor suppressor role in the esophagus and could represent a target for therapies to combat esophageal cancer.

Therapeutic agents focusing on the brain region involved in stress-induced relapse may be effective in preventing relapse in patients with alcohol use disorders.

The discovery of a previously unrecognized and pivotal role of enzyme ASL in nitric oxide production could potentially lead to new therapies for babies with pulmonary hypertension.

The Vanderbilt Digestive Disease Research Center celebrates its 10th anniversary this year with a second five-year renewal of its federal research grant.

A strain of mutant mice provide a novel model for studying glucose intolerance and gestational diabetes during pregnancy and suggest that certain molecules may be useful for therapeutic applications.

In addition to body mass index, genetic markers of obesity may provide value in predicting endometrial cancer risk.