Dexmedetomidine and delirium

The sedative dexmedetomidine, when administered during or after heart surgery, is associated with postoperative delirium and adverse outcomes.

COVID-19 complication underdiagnosed

A mysterious inflammatory syndrome linked to COVID-19 infection and first identified in children also occurs in adults, Vanderbilt researchers report.

Drug allergy labels in medical records power searches for gene-drug associations

New neurodegeneration culprit

A young woman with a puzzling neurological illness and novel genetic variant pointed investigators to a role for dysregulated protein kinase D1 in neurodegeneration.

VUMC team discovers new genetic disease

Researchers at Vanderbilt University Medical Center have discovered a new genetic disease that causes a severe form of neurogenic orthostatic hypotension, a rapid drop in blood pressure upon standing that can cause fainting.

Predictive model identifies patients for genetic testing

Patients who, perhaps unbeknownst to their health care providers, are in need of genetic testing for rare undiagnosed diseases can be identified en masse based on routine information in electronic health records (EHRs), a research team reported June 3 in the journal Nature Medicine.