Research Archive — Page 65 of 194

bacteria microbiome
April 11, 2019

How bugs overcome host defenses

Vanderbilt researchers led by Eric Skaar are probing the mechanisms bacteria use when faced with nutrient starvation — a host defense strategy called “nutritional immunity.”

By Leigh MacMillan
Laboratory pipette dispensing an amber liquid into a clear multiwell test plate, with a blurred chemical structure in the background.
March 28, 2019

Cancer’s SOS

Stephen Fesik and colleagues are advancing cancer drug discovery with the characterization of small molecules that modulate RAS, an important target for anti-cancer therapies.

By Sanjay Mishra
Stylized red heart with a stethoscope draped across it.
March 28, 2019

Cardiac dysfunction in DMD

The protein MMP7 is elevated in blood from patients with Duchenne muscular dystrophy who have cardiac dysfunction, suggesting that it may be a biomarker for heart disease severity.

By Leigh MacMillan
Manual blood pressure monitor with a blue cuff, round pressure gauge, black inflation bulb, and attached stethoscope on a white background.
March 28, 2019

Drug interaction causes hypotension

A muscle relaxing-drug and inhibitors of the metabolic enzyme CYP1A2 interact to cause severely low blood pressure and should not be co-prescribed, Vanderbilt investigators caution.

By Leigh MacMillan
Colorized illustration of a eukaryotic cell showing a central nucleus, surrounding organelles, and layered membranes against a blurred cellular background.
March 28, 2019

Unraveling endocytosis

New discoveries by Jason MacGurn and colleagues further understanding of the complex machinery that cells use take up substances from outside the cell.

By Vanderbilt Health News
Blue side profile of a human head silhouette containing interlocking colorful gears, symbolizing brain function and the workings of the human body.
March 14, 2019

New way to stimulate learning?

Vagus nerve stimulation could be beneficial for treating Alzheimer’s disease and other forms of cognitive impairment, Vanderbilt research findings suggest.

By Bill Snyder