Aliquots Archive — Page 3 of 83

Two physicians review mammogram images displayed on computer monitors in a breast imaging center; one is seated at the workstation while the other stands behind him.
June 8, 2023

An image of cancer treatment response

An MRI method developed by Vanderbilt researchers uses imaging data to derive cell size and could be added to clinical practice for better monitoring of breast cancer treatment response.

Stylized blue anatomical illustration of two kidneys connected to the central blood vessels.
May 23, 2023

Treating kidney injury before it happens

Pretreatment of an animal model with a novel compound called PHAD reduced kidney injury, suggesting it may be a good candidate for preventing kidney injury in surgical patients.

Multiple sagittal brain MRI scans arranged in a radiology film layout, with small technical labels throughout.
May 22, 2023

Neurofluid flow and Alzheimer’s disease

Vanderbilt researchers used novel MRI methods to noninvasively quantify measures of neurofluid circulation and found that hypertrophy of a site of cerebrospinal fluid egress may be related to amyloid-beta retention in Alzheimer’s disease.

skin cross section
May 18, 2023

A critical skin enzyme

Detailed studies of the enzymatic properties of PNPLA1 support the requirement for this protein in skin barrier formation.

Healthcare professional in blue scrubs holding a tablet, overlaid with glowing digital medical interface graphics including a heart-monitor waveform, hearts, lungs, and connected data points.
May 18, 2023

Billing codes aid lupus diagnosis

Vanderbilt researchers used billing codes in electronic health records to develop a “phenotype risk score” that identified established and undiagnosed people with lupus.

Stylized blue profile of a human face formed from a wireframe grid, merging with glowing circuit-board traces and digital data patterns.
May 9, 2023

Neural networks probe proteins

A machine learning method based on neural networks outperformed a mutational scanning model at identifying disease-causing mutations in an Alzheimer’s disease protein, suggesting the method could be useful for facilitating therapeutic design.