Basic Sciences

March 28, 2018

What protein is that?

An improved technology enables high-throughput protein identification in imaging mass spectrometry, aiding proteomics research.

By Leigh MacMillan
March 23, 2018

Voluntary exercise and energy balance

Non-exercise physical activity has a measurable energy expenditure, which goes down when animals engage in voluntary exercise, Vanderbilt researchers have discovered.

By Leigh MacMillan
March 22, 2018

Founders’ Celebration for Institute of Chemical Biology set for March 28

The Vanderbilt Institute of Chemical Biology (VICB) will hold a Founders’ Celebration mini-symposium on March 28 to acknowledge the contributions of its founders, Lawrence Marnett, PhD, and Ned Porter, PhD, and to celebrate 15-plus years of success as a trans-institutional scientific incubator.

By Bill Snyder
March 22, 2018

Study tracks protein’s role in stem cell function

MCL-1 is a member of the BCL-2 family of proteins important for blocking apoptosis, or programmed cell death. Many types of cancer cells escape the body’s effort to kill them by overexpressing MCL-1.

By Bill Snyder
March 15, 2018

New imaging approach offers unprecedented views of staph infection

A new integrated imaging approach makes it possible to probe the molecules involved in invasive infections and can be broadly applied to any health or disease state.

By Leigh MacMillan
close up of mans arm as he receives chemotherapy infusion
March 14, 2018

Boehringer Ingelheim and Vanderbilt University expand partnership to develop novel treatment approaches for cancer

New agreement will pursue therapies targeting MCL1 (myeloid cell leukemia 1), which is highly prevalent in many difficult-to-treat cancers.

By Bill Snyder
March 12, 2018

Long QT syndrome – revealed

Vanderbilt investigators have used sophisticated cell biological and structural techniques to “classify” mutations in potassium channels, studies that could lead to personalized treatment of heart rhythm disorders.
By Bill Snyder
March 8, 2018

Iron-sulfur “intersection”

Vanderbilt researchers have discovered an unanticipated link between sulfur and iron balance, pointing to a genetic basis for iron-deficiency anemia.
By Sanjay Mishra
March 8, 2018

VICC study sheds new light on Von Hippel-Lindau syndrome

Investigators at Vanderbilt-Ingram Cancer Center (VICC) and the Virginia Tech Carilion Research Institute (VTCRI) have revealed a gene mutation’s role in Von Hippel-Lindau syndrome, a genetically inherited disease which causes tumor growth in several organs.
By VUMC News and Communications
March 8, 2018

Lovly earns scholarship grant for lung cancer research

Christine Lovly, MD, PhD, assistant professor of Medicine at Vanderbilt, has received a $200,000 grant to support promising new research on lung cancer.
By VUMC News and Communications
February 22, 2018

Mitochondrial mutations and disease

New findings suggest that oxidative stress damages mitochondrial DNA, and they link this damage to a disease state.
By Sanjay Mishra
February 1, 2018

AAAS, chemistry society honor Lindsley’s research contributions

Craig Lindsley, PhD, co-director of the Vanderbilt Center for Neuroscience Drug Discovery (VCNDD), has been named a fellow of the Royal Society of Chemistry and elected chair-elect of the Section of Pharmaceutical Sciences of the American Association for the Advancement of Science (AAAS).
By Bill Snyder
January 31, 2018

Cell skeleton and the brush border

Vanderbilt researchers have discovered a role for microtubules — part of the cellular “skeleton” — in organizing the unique sidedness of the epithelial cells that line organs like the intestines.
By Leigh MacMillan
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