The factor FoxM1 increases the proliferation and function of insulin-producing beta cells, making it an attractive therapeutic target for diabetes.

The rigidity of the bone extracellular matrix increases the ability of tumor cells to destroy bone, suggesting new targets for anticancer drug development.

An antioxidant protein may protect against colon cancer that develops in patients with inflammatory bowel disease, suggesting new strategies for reducing colon cancer risk in these patients.

A new mouse model demonstrates that the Hhex gene – which is linked to blood cancers – is critical for normal blood cell production.

A polymer hydrogel material developed by Vanderbilt scientists improved the delivery of stem cells for heart repair.

A metabolic change in adult stem cells makes them less “fit” for regenerative heart therapies, suggesting that strategies to prevent this response may boost the therapeutic usefulness of the cells.

A novel mechanism could point to new therapies for a group of inherited diseases that share pathological features.