“Epigenetic signatures” in DNA may present an opportunity for prevention of or early intervention in childhood obesity.

A computer-based method pioneered at Vanderbilt is being used to compare subtypes of rheumatoid arthritis.

Vanderbilt investigators have discovered details about the mechanism of an important DNA repair protein that maintains genome stability.

An enzyme that builds DNA is able to insert the wrong building blocks, which could generate mutations.

Vanderbilt investigators have generated a “parts list” for the molecular machinery that duplicates DNA each time a cell divides. The research has implications for cancer therapies that target components of this machinery.

A new class of DNA repair enzyme has been discovered which demonstrates that a much broader range of damage can be removed from the double helix in ways that biologists did not think were possible.

Insights into the workings of DNA damage response proteins such as SMARCAL1 could suggest new ways to improve genome integrity and prevent cancer.