NCI

April 14, 2016

Switching breast cancer off

Signaling by a receptor that is overexpressed in aggressive forms of breast cancer has been linked to glutamine metabolism, suggesting new anti-cancer therapeutic targets.

By Marilyn Holt
April 7, 2016

Pietenpol named to NCI Blue Ribbon Panel

Jennifer Pietenpol, Ph.D., B.F. Byrd Jr. Professor of Oncology and director of Vanderbilt-Ingram Cancer Center (VICC), has been selected to serve on a Blue Ribbon Panel that will inform the scientific direction and goals at the National Cancer Institute (NCI) for Vice President Joe Biden’s National Cancer Moonshot Initiative.

By VUMC News and Communications
DNA sequence visualization
April 1, 2016

New role identified for p73 gene

The p73 gene is required for the generation of cilia – hair-like projections on cells – findings that could have implications for the study of lung diseases and sterility.

By VUMC News and Communications
March 31, 2016

Cancer prevention and poverty

A new epidemiological study supports smoking cessation and avoidance of sedentary lifestyle as cancer prevention measures.

By Paul Govern
March 17, 2016

ROCKs and cancer invasion

The rigidity of the microenvironment around cancer cells drives invasive behavior through distinct ROCK signaling pathways, which could guide the development of specific anti-invasive therapies.

By Sanjay Mishra
March 3, 2016

Melanoma response to immune therapy

Melanoma-specific expression of a certain protein identifies tumors that are more responsive to an immune therapy.

By Leigh MacMillan
February 18, 2016

Combining treatments for melanoma

Combining therapies for melanoma that induce cell senescence and that activate the immune response may improve outcomes for patients.
By Leigh MacMillan
February 10, 2016

Overcoming lung cancer drug resistance

Vanderbilt investigators have discovered a way to overcome the resistance of some lung cancers to certain targeted therapies, which could lead to more effective treatments for lung cancer patients.
By Marilyn Holt
February 4, 2016

VICC joins other major cancer centers in HPV vaccine campaign

In response to low national vaccination rates for the human papillomavirus (HPV), Vanderbilt-Ingram Cancer Center (VICC) has joined 68 of the nation’s other NCI-designated cancer centers in recommending increased HPV vaccination for the prevention of cancer.
By VUMC News and Communications
January 27, 2016

Study identifies new culprit in lung cancer development

A microRNA — a small piece of RNA involved in regulating gene expression — functions as an oncogene to drive the development of lung cancer, Vanderbilt University investigators have discovered.
By Leigh MacMillan
January 27, 2016

Wound-healing scaffolds

The elasticity of a scaffold used for healing skin wounds is a key factor in promoting regeneration versus scarring.
By Leigh MacMillan
January 22, 2016

Faulty building blocks in DNA

An enzyme that builds DNA is able to insert the wrong building blocks, which could generate mutations.
By Bill Snyder
January 8, 2016

Copying chromosome caps

Telomeres – the caps on the end of chromosomes – are a source of stress for a particular protein involved in copying DNA, a new study reports.
By Leigh MacMillan
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