Neurobiology of Disease Archive

October 6, 2022

Gene tied to childhood epilepsy

Data drawn from four unrelated patients with a childhood epilepsy syndrome — and from in vitro and in vivo studies — link novel variants in a GABA transporter gene to seizure activity, Vanderbilt researchers reported.

By Paul Govern

September 9, 2019

Astrocytes and epilepsy

A protein with important functions in astrocytes — star-shaped brain support cells — may alter neuronal excitability and contribute to seizure activity, Vanderbilt researchers report.

By Leigh MacMillan

November 8, 2018

Novel methods to treat glaucoma

Increasing a certain signaling molecule prevents the degeneration of retinal cells that are lost in glaucoma, suggesting a new way to treat this disease.

By VUMC News and Communications

February 7, 2017

Dementia linked to diet

Some memory deficits observed in Alzheimer’s disease may be due to co-morbid illnesses – not the disease itself – and may be reversed by lifestyle changes or pharmacologic interventions.

By VUMC News and Communications

February 5, 2015

Copper toxicity and Parkinson’s

A genetic predisposition to Parkinson’s disease makes neurons more vulnerable to the toxicity of heavy metals such as copper.

By Leigh MacMillan

September 30, 2014

Seizure mutation impairs receptor

Defects in the production of certain receptors are linked to the pathogenesis of genetic epilepsies and fever-induced seizures.

By Yan Su

April 20, 2012
Neuronal clues to cholesterol-defect disorder

Antioxidants may be a beneficial treatment for an inherited genetic disorder.
By Leigh MacMillan
February 1, 2012
Treatment window for genetic disorder

Treatment with a drug used to prevent organ rejection partially reverses the course of tuberous sclerosis, research in mice suggests.
By VUMC News and Communications