NIDDK Archive — Page 6 of 22

Gloved hand holding a petri dish containing red culture medium with numerous pale bacterial colonies; additional culture dishes are blurred in the background.
September 17, 2020

Probing pathogen antibiotic resistance

Understanding how bacteria evolve resistance to antibiotics and host stresses could guide the development of more effective antimicrobial therapeutics.

Assortment of colorful blister packs containing pills, including a green pack labeled with days of the week and numbered doses.
August 6, 2020

The importance of estrogen cycles

Deborah Lannigan and colleagues identify a key regulator of the estrogen receptor and suggest that its downregulation by oral contraceptives may increase oxidative stress and DNA damage, a common cause of cancer.

Soy products arranged on a wooden table, including green edamame pods, a glass of soy milk, bowls of soybeans, tofu blocks, and a small dish of dark sauce.
July 27, 2020

Soy food, metabolism and the microbiome

Consumption of soy foods may shape the microbiome and protect against hypertension only in individuals with soy-responsive microbiota, Vanderbilt researchers have discovered.

Medical illustration of the stomach and intestines, with the stomach highlighted in red and an enlarged bacterium-like form shown inside it.
July 23, 2020

Stomach bug hit-and-run

The H. pylori machinery that “injects” an oncoprotein into stomach cells contributes to the development of gastric cancer, Vanderbilt researchers demonstrate.

Stylized close-up of dark molecular ball-and-stick structures against a bright blue-white background.
July 14, 2020

New tools to study bioactive lipids

Vanderbilt researchers have identified and characterized inhibitors of an enzyme that synthesizes lipid signaling molecules with roles in energy balance, inflammation and addiction.

Illustration of purple, textured spherical particles floating against a deep blue background, with bright rays radiating from several larger particles.
July 13, 2020

“Nur” target may aid arthritis treatment

Vanderbilt immunologists have discovered that the protein Nur77 is part of a control mechanism that guards against autoimmunity in natural killer T cells.