pathology microbiology and immunology

January 5, 2021

VUMC, Case Western apply artificial intelligence to “customize” oral cancer treatment

Researchers at Vanderbilt University Medical Center and Case Western Reserve University in Cleveland have been awarded a five-year, $3.3 million grant by the National Cancer Institute to apply artificial intelligence (AI) to help customize treatment for oral cancer patients.

By Bill Snyder
December 10, 2020

Exploiting viral vulnerabilities

The isolation of human monoclonal antibodies against dangerous viruses including EEEV, Hendra and Nipah could offer new ways to treat and prevent these infections.

By Bill Snyder
C. Henrique Serezani, PhD, right, and colleagues, from left, Amondrea Blackman, Nathan Klopfenstein and Júlia Miranda Ribeiro Bazzano are studying the early events of the inflammatory response to infection.
December 10, 2020

Study details early events of inflammatory response

Vanderbilt University Medical Center investigators have identified a key molecular player in the early events of the inflammatory response to infection. The findings suggest new therapeutic possibilities for enhancing the inflammatory response to protect against pathogens and for blocking inflammation gone awry in diseases like arthritis and atherosclerosis.

By Leigh MacMillan
Alice Coogan, MD, has been named chair of the Department of Pathology, Microbiology and Immunology.
December 8, 2020

Coogan named chair of Pathology, Microbiology and Immunology

After an extensive national search Alice Coogan, MD, interim chair of the Department and professor of Pathology, Microbiology and Immunology (PM&I), has been named as the department’s next chair, effective immediately. Coogan will be the seventh chair of the department and the first female chair.

By John Howser
December 3, 2020

Team tracks sources of false positives in urine drug screens

False positives on urine drug screens are common and are frequently due to cross-reactivity of these tests to medications. Last year, Vanderbilt University Medical Center researchers Jacob Hughey, PhD, assistant professor of Biomedical Informatics, and Jennifer Colby, PhD, at that time assistant professor of Pathology, Microbiology and Immunology, devised, tested and published a method to systematically identify medications that interfere with screenings for drugs of abuse.

By Paul Govern
November 18, 2020

V Scholar Award to support Byndloss’ cancer research

Mariana Byndloss, DVM, PhD, assistant professor of Pathology, Microbiology and Immunology, has received a V Scholar Award to support her studies of the links between obesity, the gut microbiome and colorectal cancer.

By Leigh MacMillan
November 2, 2020

Frog peptides as anti-HIV microbicides

Peptides derived from the antimicrobial peptides secreted by frogs could function as microbicides to limit HIV transmission, while sparing protective vaginal bacteria.
By Leigh MacMillan
October 6, 2020

Early steps in reovirus replication

Conformational change in a reovirus surface protein modulate the virus’s attachment to host cells, Vanderbilt researchers have found.
By Leigh MacMillan
September 22, 2020

Rational vaccine design

Understanding immunity generated by smallpox vaccine may hold lessons for COVID-19 vaccine development.
By Leigh MacMillan
September 17, 2020

Probing pathogen antibiotic resistance

Understanding how bacteria evolve resistance to antibiotics and host stresses could guide the development of more effective antimicrobial therapeutics.
By Leigh MacMillan
August 25, 2020

The Vanderbilt doctor who told his story of battling AIDS on “60 Minutes”

He wrote a bestseller, was interviewed on "60 Minutes," and his story showed a more hopeful future for people infected with HIV
By Wayne Wood
August 6, 2020

The importance of estrogen cycles

Deborah Lannigan and colleagues identify a key regulator of the estrogen receptor and suggest that its downregulation by oral contraceptives may increase oxidative stress and DNA damage, a common cause of cancer.
By Sarah E. Glass
July 23, 2020

Stomach bug hit-and-run

The H. pylori machinery that “injects” an oncoprotein into stomach cells contributes to the development of gastric cancer, Vanderbilt researchers demonstrate.
By Leigh MacMillan
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