Research Archive — Page 43 of 49

December 5, 2019

Study reveals mysteries of critical brain receptor complex

Poorly functioning AMPARs have been linked to a wide range of neurological and psychiatric disorders including seizures, Alzheimer’s disease, major depression and autism spectrum disorder. Understanding how AMPARs are formed and operate is essential for the rational design of pharmacological compounds that, by tuning AMPAR activity up or down, could improve treatment of these conditions.

By Bill Snyder
November 27, 2019

Study finds ‘frozen’ fear response may underlie PTSD

To explore how fear becomes entrenched, VUMC researchers traveled down the precise neuronal pathways in the brains of mice that trigger fear responses, and which normally extinguish the behaviors once the danger has passed.

By Bill Snyder
Max Joffe, PhD, left, P. Jeffrey Conn, PhD, and colleagues are studying a new class of antidepressants that may relieve symptoms more rapidly and with fewer side effects.
November 21, 2019

Study explores potential new class of antidepressants

Researchers at VUMC have taken a major step that could ultimately facilitate development of a new class of antidepressants which may relieve symptoms more rapidly and effectively and with fewer side effects than current medications.

By Bill Snyder
November 14, 2019

SPI-Hub resource delivers intel on biomedical journals

SPI-Hub, is a new online knowledge resource that gives biomedical scientists an efficient means to identify journals in which to publish their work.

By Paul Govern
Researchers on the NCI Moonshot grant focused on hereditary cancers include (front row, from left) Natasha Celaya-Cobbs, LPN, Georgia Wiesner, MD, Sarah Bland, MPH, MBA, (back row, from left) Trent Rosenbloom, MD, Josh Peterson, MD, MPH, and Marc Beller, PMP, BA.
November 14, 2019

NCI ‘Moonshot’ grant to boost hereditary cancer identification

VUMC is leading an initiative to establish a streamlined process for collection of family health histories that could set the stage for a standardized system to make the information easily accessible.

By Tom Wilemon
October 31, 2019

Vanderbilt investigators lead effort to create map of the human kidney

Short of mandating universal diabetes treatment, regular exercise and low-calorie diets, little can be done to stem the rising tide of kidney failure — unless scientists can figure out why exactly the kidney’s filtration units, the glomeruli, stop working.

By Bill Snyder