VI4

VUMC’s Byndloss recognized for microbiome research

Mariana Byndloss, DVM, PhD, assistant professor of Pathology, Microbiology and Immunology, has been selected as a runner-up of the inaugural NOSTER & Science Microbiome Prize.

Vanderbilt Institute for Infection, Immunology and Inflammation holds third annual symposium

The Vanderbilt Institute for Infection, Immunology and Inflammation (VI4) held its third annual symposium last week as a virtual, on-line event to preserve social distancing during COVID-19.

C. diff captures blood cell cofactor to build defensive shield

Vanderbilt University Medical Center scientists have identified a C. diff protein system that senses and captures heme (part of hemoglobin) to build a protective shield that fends off threats from our immune system and antibiotics.

Jim Cassat, MD, PhD, and colleagues are studying enzymes involved in metabolism that are particularly important for Staphylococcus aureus to survive in host tissues.

Study explores how staph bacteria can survive in bone

A comprehensive evaluation of the metabolic pathways that support Staphylococcus aureus (“staph”) growth during invasive bone infections could offer new targets for treatment.

The adaptable anthrax bacterium

Vanderbilt researchers discover how anthrax bacterium defends itself against structural damage and resists the toxicity of the antimicrobial drug targocil.

Looking through MudPIT for protein interactions

The identification of novel protein interactions and sites of modification in proteins involved in mRNA translation adds to understanding of a process that is an important therapeutic target.

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