virus

October 6, 2020

Early steps in reovirus replication

Conformational change in a reovirus surface protein modulate the virus’s attachment to host cells, Vanderbilt researchers have found.

By Leigh MacMillan
May 19, 2020

Probing innate immunity

Manuel Ascano team validates an inhibitor of the cGAS-STING signaling pathway, which is important for cellular innate immunity against bacteria, viruses, and our own damaged DNA.

By Leigh MacMillan
May 14, 2020

Antibodies eye Pacific Island “fever”

Vanderbilt Vaccine Center team isolates monoclonal antibodies against Ross River virus, which causes rash, fever and debilitating muscle and joint pain lasting three to six months.

By Bill Snyder
December 13, 2018

RNA processing and antiviral immunity

John Karijolich and colleagues have discovered a link between cellular RNA processing and the innate cellular immune response to viral pathogens.

By Leigh MacMillan
July 12, 2018

Team explores diabetes drug’s ability to treat RSV infection

A drug used to treat diabetes may point to new therapies for respiratory syncytial virus (RSV) bronchiolitis — inflammation and obstruction of the lungs’ small airways. A multi-disciplinary team of Vanderbilt investigators has demonstrated that liraglutide reduces the inflammatory response to RSV infection in a mouse model of the disease.

By Leigh MacMillan
June 14, 2018

Karijolich named 2018 Pew Biomedical Scholar

John Karijolich, PhD, assistant professor of Pathology, Microbiology, and Immunology at Vanderbilt University Medical Center, has been named a Pew Biomedical Scholar by The Pew Charitable Trusts.

By Leigh MacMillan
May 23, 2018

Evolution of a deadly virus

Genomic sequences have revealed that Florida is a major source of a mosquito-borne virus that causes disease in horses and humans.
By Leigh MacMillan
May 21, 2018

New target to stop Ebola

A new Vanderbilt study suggests it may be possible to develop antibody therapies or a universal vaccine effective against multiple Ebola virus family members.
By VUMC News and Communications
May 17, 2018

Alphavirus “Achilles heel”

Targeting the protein that mosquito-borne viruses use to enter cells could be a strategy for preventing infection by multiple emerging viruses.
By Bill Snyder
January 13, 2016

Safe to snuggle with pets while home with a cold or flu, Vanderbilt infectious disease expert says

By Wayne Wood
August 20, 2014

Enzyme holds the door for influenza

Compounds developed at Vanderbilt University may offer a new way to block influenza infection.
By VUMC News and Communications
July 23, 2014

Natural killer cells don’t clear HMPV

Understanding how the immune system responds to the respiratory virus HMPV is crucial for developing vaccines and anti-viral treatments.
By Leigh MacMillan
May 27, 2014

Respiratory virus vaccine candidate

Virus-like particles containing a protein from human metapneumovirus are a promising vaccine candidate for this respiratory virus.
By Leigh MacMillan