virus Archive — Page 1 of 2

Computer-generated molecular rendering of a spherical viral particle, with purple and green surface components surrounding yellow and red internal structures.
October 6, 2020

Early steps in reovirus replication

Conformational change in a reovirus surface protein modulate the virus’s attachment to host cells, Vanderbilt researchers have found.

By Leigh MacMillan
Multiple pipettes dispense pink liquid into the wells of a laboratory microplate.
May 19, 2020

Probing innate immunity

Manuel Ascano team validates an inhibitor of the cGAS-STING signaling pathway, which is important for cellular innate immunity against bacteria, viruses, and our own damaged DNA.

By Leigh MacMillan
Close-up of a mosquito with a swollen reddish abdomen feeding on human skin against a blurred green background.
May 14, 2020

Antibodies eye Pacific Island “fever”

Vanderbilt Vaccine Center team isolates monoclonal antibodies against Ross River virus, which causes rash, fever and debilitating muscle and joint pain lasting three to six months.

By Bill Snyder
Illustration of a translucent blue cell with a purple nucleus surrounded by colorful, spiky virus-like particles and bubbles.
December 13, 2018

RNA processing and antiviral immunity

John Karijolich and colleagues have discovered a link between cellular RNA processing and the innate cellular immune response to viral pathogens.

By Leigh MacMillan
Five researchers pose in a laboratory beside a microscope and shelves of scientific supplies. From left: Kevin Niswender, R. Stokes Peebles, Tina Hartert, Lisa Bastarache, and Melissa Bloodworth.
July 12, 2018

Team explores diabetes drug’s ability to treat RSV infection

A drug used to treat diabetes may point to new therapies for respiratory syncytial virus (RSV) bronchiolitis — inflammation and obstruction of the lungs’ small airways. A multi-disciplinary team of Vanderbilt investigators has demonstrated that liraglutide reduces the inflammatory response to RSV infection in a mouse model of the disease.

By Leigh MacMillan
Portrait of a smiling man wearing a checkered shirt.
June 14, 2018

Karijolich named 2018 Pew Biomedical Scholar

John Karijolich, PhD, assistant professor of Pathology, Microbiology, and Immunology at Vanderbilt University Medical Center, has been named a Pew Biomedical Scholar by The Pew Charitable Trusts.

By Leigh MacMillan