Cancer

August 5, 2021

Clinical trial to test immunotherapy for rectal cancer

A new clinical trial seeks to determine whether immunotherapy in combination with short-course radiation followed by surgical resection could be a curative treatment for locally advanced rectal cancer.

By Tom Wilemon
August 4, 2021

Study finds genetic factor undermines H. pylori treatment

Helicobacter pylori, a stomach-dwelling bacterium, is a strong risk factor for gastric cancer, peptic ulcers and other debilitating gastrointestinal disorders. Yet efforts to eradicate it using a combination of antibiotics and proton pump inhibitors (PPIs), which suppress gastric acid production, often fail.

By Bill Snyder
July 27, 2021

Prediction models for breast cancer

Vanderbilt researchers developed new prognostic models for breast cancer outcomes and found that adding postdiagnostic weight change as a factor improves the prediction.

By Leigh MacMillan
July 26, 2021

Mood and cognition after chemotherapy

Validation of cognitive complaints appears to improve mood in patients with persistent chemotherapy-cognitive impairment, Vanderbilt researchers report.

By Emily Stembridge
July 1, 2021

Preclinical study supports rigosertib as booster to immunotherapy treatment for melanoma

A team of Vanderbilt researchers have shown in a preclinical study that the investigational drug rigosertib could be a potential booster treatment to elicit response to immunotherapies among melanoma patients.

By Tom Wilemon
June 23, 2021

Study shows benefit of scheduling lung screens with mammograms

Women who are longtime smokers could potentially save their lives by undergoing lung screens on the same day they schedule mammograms, according to a study by Vanderbilt researchers published in the Journal of Medical Screening.

By Tom Wilemon
June 22, 2021

Treating metastatic prostate cancer

An indirect comparative effectiveness study using published data suggests that the targeted therapy olaparib should be re-evaluated for treating metastatic prostate cancer.
By Leigh MacMillan
May 27, 2021

Vanderbilt-Ingram Cancer Center calls for action to get cancer-preventing HPV vaccination back on track

A significant reduction in annual well visits and immunizations during the COVID-19 pandemic has led to a vaccination gap among U.S. children and adolescents, especially with the human papillomavirus (HPV) vaccine for cancer prevention.
By VUMC News and Communications
May 26, 2021

Vanderbilt researchers present new data on clinical trials at ASCO 2021

Vanderbilt-Ingram Cancer Center researchers will present data on clinical trials involving targeted therapies, immunotherapies and drug combination synergies at the 2021 American Society of Clinical Oncology Annual Meeting, June 4-8. The meeting is a virtual event this year.
By Tom Wilemon
May 24, 2021

Analysis reveals macrophages associated with kidney cancer recurrence

A white blood cell, the TREM2/APOE/C1Q-positive macrophage, has been identified as a potential biomarker to predict recurrence of the most common type of kidney cancer and as a possible target for drug development.
By Tom Wilemon
May 13, 2021

People at high genetic risk for colorectal cancer benefit more from lifestyle changes

People with a high polygenic risk score for colorectal cancer could benefit more at preventing the disease by leading healthy lifestyles than those at lower genetic risk, according to a study by Vanderbilt researchers published in the April issue of The American Journal of Clinical Nutrition.
By Tom Wilemon
April 29, 2021

Songs written by Palliative Care Unit caregivers reflect uncertain times and offer a reminder: “Take Good Care”

Five songs providing a snapshot of how the pandemic year felt on the patient care front lines
By Matt Batcheldor
April 22, 2021

Vanderbilt Wilson County Hospital President Hinesley departing VUMC to join MUSC

Julian “Jay” Hinesley III, MHA, President of Vanderbilt Wilson County Hospital (VWCH), is leaving his role with Vanderbilt University Medical Center to join the Medical University of South Carolina (MUSC) as Chief Executive Officer for MUSC Health’s Florence Division in Florence, South Carolina, where he will lead three hospitals located in Florence and adjacent communities. He will depart VWCH and VUMC on April 30.
By John Howser