Genetics & Genomics

Photo caption: Jonathan Mosley, MD, PhD, left, Scott Borinstein, MD, PhD, John Shelley, and Vivian Kawai, MD, MPH, are studying how genetic variation not related to disease affects clinical decisions. (photo by Susan Urmy)
June 3, 2024

Genetic variation associated with low white blood cell count impacts clinical decisions

People whose white blood cell levels are near the edge of the “healthy” reference range will hit a clinical decision point that has consequences such as diagnostic procedures and altered treatments.

By Leigh MacMillan
(iStock)
May 21, 2024

NIH grant supports effort to build expertise in genetic epidemiology research in Vietnam

V2-GENE, the Vanderbilt-Vietnam Genetic Epidemiology Training Program, will develop a team of researchers and educators to lead genetic epidemiology research of noncommunicable diseases across the lifespan in Vietnam.

By Leigh MacMillan
(iStock)
May 15, 2024

Treatment-resistant depression linked to body mass index: study

Genetic factors are a small but significant contributor to severe depression that does not respond to standard therapy, according to researchers at Vanderbilt University Medical Center and Massachusetts General Hospital.

By Bill Snyder
(iStock)
May 14, 2024

Breast cancer risk variants identified for women of African ancestry

A study led by researchers from Vanderbilt-Ingram Cancer Center sheds light on some of the genetic variants that make breast cancer more deadly for women of African ancestry and significantly reduces the disparity in knowledge for assessing their genomic risk factors.

By Tom Wilemon
Alexander Bick, MD, PhD
May 1, 2024

VUMC’s Alexander Bick receives a “healthy aging” research award

Vanderbilt’s Alexander Bick, MD, PhD, has received a Hevolution/AFAR New Investigator Award in Aging Biology and Geroscience Research from the American Federation for Aging Research (AFAR) and Hevolution Foundation.

By Bill Snyder
(iStock image)
May 1, 2024

Study finds 500 new blood pressure genes

An analysis of the genomes of more than 1 million people of European ancestry, conducted by several of the world’s leading genomic centers, including Vanderbilt University Medical Center, has identified more than 2,000 independent genetic signals for blood pressure.

By Bill Snyder
April 1, 2024

Cell-specific variations in gene regulation may be key to treating pulmonary fibrosis

An international research team co-led by Vanderbilt University Medical Center has revealed how variations in gene regulation in different cell types drive pulmonary fibrosis, a progressive respiratory disorder characterized by scarring and loss of functional lung tissue.
By Bill Snyder
March 27, 2024

Higher genetic risk of obesity means working out harder for same results 

Study authors used activity, clinical and genetic data from the National Institutes of Health’s All of Us Research Program to explore the association of genetic risk of higher body mass index and the level of physical activity needed to reduce incident obesity. 
By Craig Boerner
March 26, 2024

Beethoven’s genes reveal low predisposition for beat synchronization

What the exceptional composer's DNA tells us about genetics
By Craig Boerner
March 8, 2024

Douglas Ruderfer to direct new Center for Digital Genomic Medicine

Douglas Ruderfer, PhD, whose research at Vanderbilt University Medical Center explores the intersection of genomics, biomedical informatics and psychiatry, has been named director of a newly established Center for Digital Genomic Medicine.
By Bill Snyder
February 21, 2024

Large, diverse genetic study of glaucoma implicates vascular and cancer-related genes

An international genetic study using multiancestry biobanks has identified novel genetic locations associated with primary open-angle glaucoma, the most common type of glaucoma and the leading cause of irreversible blindness globally.
By Leigh MacMillan
February 19, 2024

VUMC part of major step to achieving precision medicine

An analysis of genomic data from nearly 250,000 participants in the National Institutes of Health’s All of Us Research Program has identified more than 275 million previously unreported genetic variations, nearly 4 million of which have potential health consequences.
By Bill Snyder
January 5, 2024

The Alliance for Genomic Discovery welcomes Bristol Myers Squibb, GSK and Novo Nordisk

Bristol Myers Squibb, GSK and Novo Nordisk are the newest members of the Alliance for Genomic Discovery.
1 2 3 4 5 … 13