Alzheimer’s disease

July 17, 2023

Alzheimer’s genetic risk tracked across sex, race

A Vanderbilt study of genetic risks for cognitive impairment later in life uses data from 32,426 research participants ages 60 and older to elaborate these risks across sex and across the intersection of sex and race.

By Paul Govern
June 12, 2023

Images predict functional decline

MRI brain scans at baseline for study participants 60 and older — who were free of clinical dementia at study entry — predicted a decline in independent function five years later.

By Paul Govern
May 22, 2023

Neurofluid flow and Alzheimer’s disease

Vanderbilt researchers used novel MRI methods to noninvasively quantify measures of neurofluid circulation and found that hypertrophy of a site of cerebrospinal fluid egress may be related to amyloid-beta retention in Alzheimer’s disease.

By Leigh MacMillan
May 9, 2023

Neural networks probe proteins

A machine learning method based on neural networks outperformed a mutational scanning model at identifying disease-causing mutations in an Alzheimer’s disease protein, suggesting the method could be useful for facilitating therapeutic design.

By Leigh MacMillan
November 8, 2022

Alzheimer’s risk factor and cognition

Vanderbilt researchers found that a protein with roles in innate immunity worsens memory at baseline in carriers of APOE-e4, the strongest genetic risk factor for Alzheimer’s disease, further implicating neuroinflammation in cognitive decline.

By Leigh MacMillan
Networked dots in the shape of a brain
October 3, 2022

Minority patients less likely to have amyloid plaques necessary for Alzheimer’s treatments

Fewer Black, Hispanic and Asian patients meet biomarker qualifications for landmark treatments that may slow the progression of Alzheimer’s disease by targeting amyloid plaques, according to new findings published in JAMA Neurology.

By Holly Fletcher
September 15, 2022

Gifts bolster otolaryngology, Alzheimer’s disease programs

Herbert Christopher, a grateful Otolaryngology–Head and Neck Surgery patient who received cochlear hearing implants from David Haynes, MD, has funded the training of otolaryngology fellows and leaders in Alzheimer’s disease care through several outright endowed gifts and additional gift planning with his estate.
By Emily Stembridge
June 21, 2022

Today Show: Vanderbilt Memory and Alzheimer’s Center makes national push for clinical study enrollment. You can help.

The Today Show’s Maria Shriver spotlighted a landmark, years-long study into the connection between heart health and Alzheimer’s disease, and the urgency to boost study enrollment—particularly among people of color who are disproportionally impacted yet historically underrepresented in research.
By Holly Fletcher
April 26, 2022

New Clinician Spotlight: Aaron McMurtray

Specializing in dementia and Alzheimer’s disease, neurologist Aaron McMurtray, MD, PhD, recently joined Vanderbilt University Medical Center as associate professor of Neurology.
By VUMC News and Communications
April 21, 2022

Kalousová, Bolton receive Alzheimer’s Association awards

Vanderbilt's Lucie Kalousová, PhD, and Corey Bolton, PsyD, have received research awards from the Alzheimer’s Association.
By Paul Govern
April 7, 2022

Event highlights research on Alzheimer’s disease

The third annual Vanderbilt Alzheimer’s Disease Research Day featured numerous presentations and concluded with a keynote address by Suzanne Craft, PhD, director of the Alzheimer’s Disease Research Center at Wake Forest University.
By Paul Govern
February 24, 2022

PET imaging probe for Alzheimer’s disease

Vanderbilt researchers report on a new PET imaging probe that will be useful for exploring Alzheimer’s disease pathology.
By Leigh MacMillan
January 5, 2022

Vanderbilt Kennedy Center to host Jan. 25 workshop on Down syndrome and Alzheimer’s disease

By VUMC News and Communications
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