Alzheimer’s disease

January 12, 2018

BOLD view of white matter

Vanderbilt investigators have discovered that functional MRI detects neural activity in both gray and white matter in the brain, suggesting new ways to investigate diseases such as Alzheimer’s and multiple sclerosis.

By Bill Snyder
December 1, 2017

Vitamin C deficiency and mitochondrial dysfunction in Alzheimer’s disease

Recent findings suggest that vitamin C deficiency could contribute to Alzheimer’s disease, suggesting that avoiding deficiency through diet and supplementation could protect against disease onset.

By VUMC News and Communications
Elderly woman looking out window
November 8, 2017

Research links heart function to brain’s memory center

Research by a team of Vanderbilt University Medical Center (VUMC) scientists suggests that older people whose hearts pump less blood have blood flow reductions in the temporal lobe regions of the brain, where Alzheimer’s pathology first begins.

By Tom Wilemon
October 16, 2017

Gender, pain and dementia

Understanding sex differences in pain perception could lead to more targeted and effective pain assessment and management strategies in older adults with Alzheimer’s disease.

By Bill Snyder
September 5, 2017

Pain and Alzheimer’s disease

Clinicians should use a structured interview in people with Alzheimer’s disease to identify pain that might be otherwise overlooked.

By VUMC News and Communications
elderly Asian mother and adult daughter
August 7, 2017

Vanderbilt begins Phase 1 trials of new Alzheimer’s drug

Developed at Vanderbilt, VU319 is designed to precisely target a specific neuron receptor associated with cognitive function while avoiding potentially dangerous side effects.

By Bill Snyder
April 27, 2017

Protein structure may aid in treating Alzheimer’s disease

A new protein structure may guide the development of Alzheimer's therapeutics.
By Leigh MacMillan
February 7, 2017

Dementia linked to diet

Some memory deficits observed in Alzheimer’s disease may be due to co-morbid illnesses – not the disease itself – and may be reversed by lifestyle changes or pharmacologic interventions.
By VUMC News and Communications
January 25, 2017

Learn about Alzheimer’s disease and dementia research at public forum

Vanderbilt researchers will discuss their groundbreaking studies on Alzheimer’s disease and dementia at an upcoming forum, and the public is invited to attend.
By VUMC News and Communications
December 27, 2016

Investigational new drug for Alzheimer’s scheduled for first study in humans

Vanderbilt University scientists have received notification from the U.S. Food and Drug Administration that testing in humans may proceed for an investigational new drug for Alzheimer's disease after more than 10 years of research by scientists at Vanderbilt University and Vanderbilt University Medical Center.
By Craig Boerner
November 10, 2016

Alzheimer’s study establishes way to measure resilience

Vanderbilt researchers have established a new measure of resilience to cognitive impairment in people with asymptomatic Alzheimer’s disease.
By Tom Wilemon
July 12, 2016

Vanderbilt study shows people with Alzheimer’s have lower ability to perceive pain

People with Alzheimer’s disease don’t perceive pain as readily as healthy older adults, and this may lead to delays and underreporting of pain. This alteration in pain detection may be one reason that people with Alzheimer’s disease and pain tend to be undermedicated and suffer unnecessarily, a trans-institutional group of Vanderbilt researchers reported recently in BMC Medicine.
By VUMC News and Communications
June 2, 2016

Alzheimer’s risk gene in younger adults

A genetic risk factor for Alzheimer’s disease in later life appears to benefit younger adults as they age.
By Leigh MacMillan