Alzheimer’s disease

August 30, 2018

Study links aortic stiffness with lower cerebral blood flow

Greater aortic stiffness is related to lower cerebral blood flow, especially among individuals with increased genetic predisposition to Alzheimer’s disease, according to research from Vanderbilt University Medical Center.

By Tom Wilemon
May 7, 2018

Study provides robust evidence of sex differences with Alzheimer’s gene

The APOE gene, the strongest genetic risk factor for Alzheimer’s disease, may play a more prominent role in disease development among women than men, according to new research from the Vanderbilt Memory and Alzheimer’s Center.

By Tom Wilemon
March 27, 2018

Alzheimer’s proteins in ICU survivors

The cognitive impairment that affects patients who survive a stay in the ICU does not appear to have a similar mechanism to Alzheimer’s disease, Vanderbilt researchers have discovered.

By Meredith Jackson
January 12, 2018

BOLD view of white matter

Vanderbilt investigators have discovered that functional MRI detects neural activity in both gray and white matter in the brain, suggesting new ways to investigate diseases such as Alzheimer’s and multiple sclerosis.

By Bill Snyder
December 1, 2017

Vitamin C deficiency and mitochondrial dysfunction in Alzheimer’s disease

Recent findings suggest that vitamin C deficiency could contribute to Alzheimer’s disease, suggesting that avoiding deficiency through diet and supplementation could protect against disease onset.

By VUMC News and Communications
Elderly woman looking out window
November 8, 2017

Research links heart function to brain’s memory center

Research by a team of Vanderbilt University Medical Center (VUMC) scientists suggests that older people whose hearts pump less blood have blood flow reductions in the temporal lobe regions of the brain, where Alzheimer’s pathology first begins.

By Tom Wilemon
October 16, 2017

Gender, pain and dementia

Understanding sex differences in pain perception could lead to more targeted and effective pain assessment and management strategies in older adults with Alzheimer’s disease.
By Bill Snyder
September 5, 2017

Pain and Alzheimer’s disease

Clinicians should use a structured interview in people with Alzheimer’s disease to identify pain that might be otherwise overlooked.
By VUMC News and Communications
August 7, 2017

Vanderbilt begins Phase 1 trials of new Alzheimer’s drug

Developed at Vanderbilt, VU319 is designed to precisely target a specific neuron receptor associated with cognitive function while avoiding potentially dangerous side effects.
By Bill Snyder
April 27, 2017

Protein structure may aid in treating Alzheimer’s disease

A new protein structure may guide the development of Alzheimer's therapeutics.
By Leigh MacMillan
February 7, 2017

Dementia linked to diet

Some memory deficits observed in Alzheimer’s disease may be due to co-morbid illnesses – not the disease itself – and may be reversed by lifestyle changes or pharmacologic interventions.
By VUMC News and Communications
January 25, 2017

Learn about Alzheimer’s disease and dementia research at public forum

Vanderbilt researchers will discuss their groundbreaking studies on Alzheimer’s disease and dementia at an upcoming forum, and the public is invited to attend.
By VUMC News and Communications
December 27, 2016

Investigational new drug for Alzheimer’s scheduled for first study in humans

Vanderbilt University scientists have received notification from the U.S. Food and Drug Administration that testing in humans may proceed for an investigational new drug for Alzheimer's disease after more than 10 years of research by scientists at Vanderbilt University and Vanderbilt University Medical Center.
By Craig Boerner