Angela Jefferson Archives
Arterial stiffening linked to Alzheimer’s disease
Jul. 15, 2021—A research team from Vanderbilt University Medical Center reports in Neurology that greater stiffening of the aorta, the main artery in the human body, is associated in older adults with increased Alzheimer’s disease (AD) pathology as reflected in a range of neurochemical indicators measured in cerebrospinal fluid.
VUMC forms center focused on Alzheimer’s and related dementias
Oct. 1, 2020—Leaders at Vanderbilt University Medical Center have announced that the Vanderbilt Memory and Alzheimer’s Center (VMAC), currently housed in the Department of Neurology, will become a freestanding institutional center.
VUMC to lay groundwork for Tennessee’s first federally funded Alzheimer’s Disease Research Center
Sep. 10, 2020—Angela Jefferson, PhD, professor of Neurology and director of the Vanderbilt Memory and Alzheimer’s Center, has been awarded a $3.7 million, three-year grant from the National Institute on Aging (NIA) to support establishment of a prospective NIA-funded Alzheimer’s Disease Research Center (ADRC) at Vanderbilt University Medical Center.
Grant supports research on abnormal brain aging
Aug. 6, 2020—With the aid of an $18.2 million, five-year grant renewal from the National Institute on Aging, the Vanderbilt Memory and Aging Project (VMAP) will advance interdisciplinary research into abnormal brain aging and cognitive decline in older adults, with continuing emphasis on the role of blood flow changes in the heart and brain.
New study examines Alzheimer’s disease images and molecular biomarkers
May. 7, 2020—Alzheimer’s disease (AD) involves distinctive wasting away of certain brain regions, such that medical imaging of these regions can distinguish the disease from other subtypes of dementia.
Small vessel disease MRI marker linked to worse cognitive health in older adults
Mar. 21, 2019—Enlarged perivascular spaces, which are commonly seen on brain MRIs in older adults, have important associations with worse cognitive performance, particularly information processing speed and executive function, according to a new study that challenges historical consideration that perivascular spaces are a harmless imaging marker.
Probing the pathology of impaired cognition
Oct. 25, 2018—Detecting the neuropathology underlying cognitive impairment by lead to new targeted therapies.
Study links aortic stiffness with lower cerebral blood flow
Aug. 30, 2018—Greater aortic stiffness is related to lower cerebral blood flow, especially among individuals with increased genetic predisposition to Alzheimer’s disease, according to research from Vanderbilt University Medical Center.
Research links heart function to brain’s memory center
Nov. 8, 2017—Research by a team of Vanderbilt University Medical Center (VUMC) scientists suggests that older people whose hearts pump less blood have blood flow reductions in the temporal lobe regions of the brain, where Alzheimer’s pathology first begins.
Study shows poor heart function could be major Alzheimer’s disease risk
Mar. 3, 2015—A healthier heart could prevent Alzheimer’s disease, according to new research at Vanderbilt University Medical Center.
Cognitive complaints, Alzheimer’s risk studied
Aug. 1, 2013—A study of cognitive complaints in older adults showed that memory concerns from both the patient and an informant was most predictive of converting to Alzheimer’s disease or dementia within three years.
