In 2008 at VUMC there were a group of doctors trying something unheard of on a handful of patients who signed up for their study. Half would receive deep brain stimulation (DBS) surgery in attempt to slow the progression of their early-stage Parkinson’s disease, and the others would not.

The funds will help launch a clinical trial in the U.S. with one of the therapies and compare it with another therapy from an ongoing clinical trial in Japan.

Participants may be able to join this study if they have Down syndrome, are between 35 and 50 years old and have a study partner willing to attend all study visits.

Findings from NIH-supported clinical trial suggest that intravenous acetaminophen has the greatest benefit in the sickest patients.

Developed in a region with the world’s highest HIV prevalence, this study design and intervention has the potential to impact testing uptake among a “hidden population” by mobilizing trained healers, who vastly outnumber allopathic care providers in South Africa.

A multicenter study led by Vanderbilt University Medical Center and Lipscomb University College of Pharmacy in Nashville has identified a potential new treatment for acute heart failure, a leading cause of hospitalization and death.

VUMC is acrawl with statistical design, bias detection and analysis that’s recognized with $532 million in federal and nonfederal research support.