clinical trial Archive — Page 7 of 16

October 17, 2023

Tirzepatide trial shows additional 21.1% weight loss following intensive lifestyle intervention

A Vanderbilt clinical trial evaluating the injectable prescription medication tirzepatide, showed an additional 21.1% weight loss after intensive lifestyle intervention in adults with obesity or who were overweight with weight-related comorbidities, excluding Type 2 diabetes.

Wesley Self, MD, MPH
October 17, 2023

How biostatistics saves lives: the Vanderbilt experience

Biostatisticians at VUMC have played a pivotal role in the redesign of clinical trials that rigorously and rapidly determine the effectiveness of life-saving treatments for acutely ill patients.

October 16, 2023

ICU antibiotics may be safe for kidneys

A Vanderbilt study found that two antibiotics thought to cause kidney failure in ICU patients with a severe bacterial infection, especially when combined with another antibiotic, may be safer for the kidneys than previously reported.

Sharon Kantanie, center, participated in the study of a drug that reduced soft-tissue flare-ups and the prevented new areas of abnormal bone formation. With her are, from left, Emily Shardelow, clinical/translational research coordinator; Sharon’s parents, Mary and Stan Kantanie; Margo Black, MSN, manager of research projects for Metabolic Bone Disorders; and Kathryn Dahir, MD, professor of Endocrinology and Diabetes. (photo by Erin O. Smith)
September 28, 2023

Drug trial shows reduced abnormal bone formation in those with fibrodysplasia ossificans progressiva

A Vanderbilt clinical trial evaluating the investigational drug garetosmab has shown that it reduced soft-tissue flare-ups significantly and prevented new areas of abnormal bone formation in patients with fibrodysplasia ossificans progressiva.

September 20, 2023

Surgeons to lead multisite study of procedure to limit blood loss by partially blocking aorta

Vanderbilt care surgeons are leading a two-year, multicenter observational study of a minimally invasive technique to control life-threatening blood loss by inserting a balloon inside the aorta to restrict blood flow below the heart.

A probe-based system developed by a team at Vanderbilt University and Vanderbilt University Medical Center uses near-infrared autofluorescence to confirm the location of parathyroid tissue during surgery.
August 24, 2023

Study shows Vanderbilt-developed technology assists surgeons in identifying parathyroids

A team of surgeons and biomedical engineers have shown the use of probe-based near infrared autofluorescence technology helps confirm the identification of parathyroid glands during endocrine surgery