cystic fibrosis Archives
EHRs, biobanks and Mendelian diseases
Apr. 30, 2020—Electronic health records and biobanks can be effectively combined to detect and study Mendelian diseases such as cystic fibrosis.
Clarksville boy bounces back after COVID-19 infection
Apr. 29, 2020—After a month of cough, off-and-on fever, not feeling well and isolation, Joseph “Jo Jo” Bostain is back to bouncing on his trampoline, reading Harry Potter books and planting flowers outside his Clarksville home.
Adults with cystic fibrosis face diabetes risk, spur new research
Aug. 16, 2018—Although cystic fibrosis (CF) has long been known as a pediatric disease, physicians and scientists at Vanderbilt University Medical Center are providing specialized care for an ever-growing population of adults with CF, as well as conducting targeted research expected to improve treatment for these patients.
VUMC investigators find pathogens work together to infect host
Nov. 3, 2016—Pseudomonas aeruginosa and Staphylococcus aureus — two pathogens that frequently co-infect the lungs of patients with cystic fibrosis — appear to cooperate with each other, Vanderbilt investigators have discovered. When pseudomonas is starved for metal by the host, it shuts down the production of factors that would normally kill staph, promoting a co-infection.
Study reveals new clues to cystic fibrosis ‘gender gap’
Sep. 15, 2016—A research team led by structural biologists from Vanderbilt University has come up with the first detailed molecular explanation for a factor that may contribute to the so-called cystic fibrosis (CF) “gender gap.”
How ABC transporters move molecules
Jun. 13, 2014—New views of how transporters move molecules across cell membranes are key to understanding how these proteins impact tumor cell drug resistance and inherited diseases such as cystic fibrosis.
Reversing lipid woes in cystic fibrosis
Mar. 3, 2012—Abnormal levels of fatty acids in the blood and tissues of patients with cystic fibrosis may be reversed by supplementation with the fatty acids DHA and EPA.