Vanderbilt, Zambia researchers find delirium in hospitalized patients linked to mortality, disability in Sub-Saharan Africa
Feb. 11, 2021—Delirium, a form of acute brain dysfunction, is widespread in critically ill patients in lower resourced hospitals, and the duration of delirium predicted both mortality and disability at six months after discharge, according to a study published in PLOS ONE.
Jan. 8, 2021—COVID-19 patients admitted to intensive care in the early months of the pandemic were subject to a significantly higher burden of delirium and coma than is typically found in patients with acute respiratory failure. Choice of sedative medications and curbs on family visitation played a role in increasing acute brain dysfunction for these patients.
May. 27, 2020—Vanderbilt University Medical Center will study adult survivors of medical and surgical intensive care at high risk for long-term cognitive impairment to see if computerized cognitive rehabilitation (CCR) is effective in improving cognition in ICU survivors who often have trouble doing complex tasks, maintaining their finances and staying employed.
Jan. 8, 2020—Intensive care unit delirium, a fertile area of clinical research and patient care innovation associated with VUMC, is beginning to reshape how commercial electronic health record systems are engineered with regard to intensive care.
Mar. 7, 2019—For years Kristina Betters, MD, assistant professor of Pediatric Critical Care at Monroe Carell Jr. Children’s Hospital at Vanderbilt, has been aware of the value of getting patients in the intensive care unit (ICU) moving during their critical illnesses to prevent muscle breakdown, weakness and delirium.
Oct. 22, 2018—Critically ill patients are not benefiting from antipsychotic medications that have been used to treat delirium in intensive care units (ICUs) for more than four decades, according to a study released today in the New England Journal of Medicine.
Oct. 4, 2018—Millions of patients in intensive care units each year develop delirium during their hospitalization and often leave the hospital with cognitive deficits similar to those suffering from traumatic brain injury or mild Alzheimer’s disease.
Mar. 29, 2018—A Vanderbilt study of more than 1,000 intensive care unit patients around the country, nearly three-fourths of whom experienced delirium, showed that many drugs given to sedate patients in the ICU are actually increasing their chances of — and duration of — delirium instead of helping them recover.
Dec. 7, 2017—Catatonia, a syndrome of motor, emotional and behavioral abnormalities frequently characterized by muscular rigidity and a trance-like mental stupor and at times manifesting with great excitement or agitation, can occur during a critical illness and appear similar to delirium. But the management strategies are vastly different.